Human Exposure To Halogenated Aromatic Compounds

利用台湾死亡登记处和中毒受害者普查的数据，我们比较了PCB暴露发生后28年的死亡率。 这是第一次出现癌症死亡率过高的情况，特别是胃癌。 这增加了几个公共卫生组织关于这些化学品对人类致癌的评估的一致性。 系统性红斑狼疮的死亡人数也出乎意料地多，这在暴露于类似化学物质的其他队列中还没有发现。 利用北卡罗来纳州的数据，我们发现，通过应用纵向技术分析我们的生长数据，那些将继续青春期提前的女孩在6-12个月大的时候比其他女孩重。 男孩也有同样的模式，但不那么明显。

Using data from the Taiwanese death registry and the census of victims of the poisoning, we compared mortality at 28 years after the PCB exposure occurred. For the first time, there was excess mortality from cancer, specifically stomach cancer. This adds consistency to the evaluations made by several public health organizations that these chemicals are carcinogenic for humans. There was also an unexpected excess of deaths from systemic lupus, which has not been seen in other cohorts exposed to similar chemicals. Using the North Carolina data, we found that, by applying longitudinal techniques to analysis of our growth data, that girls who would go on the have early puberty were heavier than other girls by the time they were 6-12 months old. Boys had the same pattern, but it was less pronounced.