FUNCTIONAL NEUROANATOMY OF THE BASOLATERAL AMYGDALA

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是确定内在膜，和本地网络的属性，有助于振荡活动的基底外侧杏仁核投射神经元的合奏。我们开始绘制大鼠和灵长类动物基底外侧杏仁核中定义的子区域神经元的生理特性。 虽然已知BLA中间神经元是异质细胞群，但传统上该区域中的投射神经元被集中在一起作为同源单元。 我们已经从大鼠和灵长类动物中收集了数据，这些数据直接与BLA投射神经元功能特性的同质性概念相矛盾。 我们使用多因子分析结合K-means聚类分析来梳理不同的BLA投射神经元亚群。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goals of this study are to identify intrinsic membrane, and local network properties that contribute to oscillatory activity in ensembles of basolateral amygdala projection neurons. We began to map the physiological properties of neurons in defined sub-regions of the rat and primate basolateral amygdala. While BLA interneurons are known to be a heterogeneous cell population, traditionally projection neurons in this region have been lumped together as a homologous unit. We have collected data from both the rat and primate that directly contradicts the notion of homogeneity in the functional properties of BLA projections neurons. We are using multiple factorial analyses in conjunction with K-means cluster analysis to tease apart distinct subpopulations of BLA projection neurons.