AIDS Clean Cage Storage Facility

描述（由申请人提供）：本申请来自位于加州大学戴维斯分校（UCD）的加州国家灵长类动物研究中心（CNPRC），旨在通过有限竞争获得联邦资金597，454美元：校外研究设施改善计划（C 06）用于艾滋病清洁笼储存设施项目。该申请旨在为增加清洁的笼子储存空间提供资金，以支持两个新的模块化动物建筑和现有的模块化建筑，在这些建筑中进行艾滋病相关和传染病研究。这将确保符合《实验室动物护理和使用指南》第八版关于清洁笼储存的指令，以确保开发有效的HIV疫苗和疗法所需的可靠和可预测的非人灵长类动物（NHP）模型。拟议的清洁笼存储设施是CNPRC将室内动物饲养区划分为传染病区和非传染病区的更大计划的一部分，以通过消除跨越主要交通走廊的笼运输来改善职业安全，并提高运营效率。每个区域将有自己的室内动物饲养空间、笼舍清洗和清洁笼舍储存设施。干净的笼子储存设施是完成这一计划的最后一个组成部分，是艾滋病相关研究的有效和高效运作的一个组成部分，两个模块化建筑物提供了144个国家卫生中心的额外容量。这项请求的具体规定如下： * 56个滚动机架的清洁笼存储容量（每个机架4个笼） * 在CNPRC内建立一个完全分隔的艾滋病/ID研究和支持区 该提案的目标是增加提供笼子储存所需的基础设施能力，以促进艾滋病相关研究的增长，并提高业务效率，减少将这些笼子用于研究的实际风险和货币成本。

DESCRIPTION (provided by applicant): This application from the California National Primate Research Center (CNPRC) located at the University of California, Davis (UCD), seeks to obtain federal funding in the amount of $597,454 through the Limited Competition: Extramural Research Facilities Improvement Program (C06) for the AIDS Clean Cage Storage Facility Project. This request seeks to fund the addition of clean cage storage space necessary to support two new modular animal buildings and existing modular buildings in which AIDS-related and infectious disease research is conducted. This will assure compliance with the Guide for the Care and Use of Laboratory Animals, eighth edition in its directive for clean cage storage to ensure reliable and predictable nonhuman primate (NHP) models for the development of effective HIV vaccines and therapies. The proposed clean cage storage facility is part of a larger plan to segment the CNPRC's indoor animal housing areas into infectious disease and non-infectious disease zones in order to improve occupational safety by eliminating the transportation of caging across major traffic corridors, and improve operational efficiencies. Each zone will have its own indoor animal housing space, cage wash, and clean cage storage facility. The clean cage storage facility is the final component to accomplishing this plan and is integral to the effective and efficient operation of AIDS-related research with the additional capacity of 144 NHPs being provided by the two modular buildings. The specific provisions of this request are as follows: * Clean cage storage capacity for 56 rolling racks (4 cages per rack) * A fully segmented zone for AIDS/ID research and support within the CNPRC The goal of this proposal is to increase the infrastructure capacity necessary to provide cage storage to facilitate growth in AIDS-related research and to improve operational efficiencies that decrease the physical risk and monetary cost of delivering those cages to research.