Research Training in Gastroenterology and Hepatology

T32 DK067872的竞争续签申请，胃肠病和肝脏病学的研究培训， 代表马里兰大学提交的巴尔的摩大学(UMB)请求为3名博士前提供5年的支持 博士后(MD、PhD、MD/PhD)实习生4人。该计划的目标是寻找和培养有才华的实习生 在学术界、政府或行业的研究和/或领导职业生涯，通过提供综合的、相互的 强调三个专业之一的基础或临床和翻译科学培训的学科课程 主要领域：(1)胃肠粘膜生物学和信号，(2)肠道微生物组，免疫学和遗传学， (3)肝胆疾病。由教师导师代表的UMB实体拥有强大的联邦资金 项目组合横跨学校、部门，并组织了研究中心和机构，包括学校 医学系(内科、儿科、外科、流行病学及公共卫生、微生物学及 免疫学、生物化学和分子生物学)和药剂学(药学系)， 疫苗开发和全球健康中心和基因组科学研究所。全面 培训机会允许博士后学员获得博士或医学博士/博士学位，博士后学员获得 获得硕士、公共卫生硕士或博士学位。在专家导师的监督下，该培训计划旨在 使学员能够开发假说、设计和执行基础或临床研究以检验这些假说， 成为至少一个与消化或肝脏疾病相关的实质性领域的专家，发展口头和书面能力 演讲技巧，掌握负责任进行研究的原则，并为过渡到职业生涯做准备 主要研究胃肠道和肝胆系统的生物学和病理生物学。基础和临床 三个重点领域的翻译科学培训(GI粘膜生物学和信号；肠道微生物组， 免疫学和遗传学；肝胆疾病)，由经验丰富的高生产率导演 在研究轨道内和研究轨道之间进行互动的导师。自2005年成立以来，这项T32计划已经 非常成功；所有培训职位始终满员，学员留存率为100%，工作效率为 以出版物来衡量，授予高级学位和职业成就都是出类拔萃的。全 完成博士学位培训的博士后实习生和几乎所有医学博士后实习生 拥有或将获得高级学位(理科硕士、公共卫生硕士或博士)。这个T32程序仍然非常出色 多样化，满足社会需要，解决生物医学研究和学术界代表性不足的问题；三分之二 我们培训的学员中有五分之一是女性，还有五分之一是拉丁裔或非裔美国人。以前的实习生获得学历 为联邦机构(NIH和FDA)或行业任命教师或进行研究，竞争成功 申请联邦资金，并在学术界获得领导职位。值得注意的是，通过吸引有才华的实习生和 从其他学科到基础和以患者为中心的消化系统疾病和肝脏研究的研究人员，这一T32 该计划为UMB的临床、教育和科学界增加了巨大的价值。

This competitive renewal application for T32 DK067872, Research Training in Gastroenterology and Hepatology, submitted on behalf of the University of Maryland, Baltimore (UMB) requests 5 years of support for 3 predoctoral and 4 postdoctoral (MD, PhD, MD/PhD) trainees. Program goals are to seek and prepare talented trainees for research and/or leadership careers in academia, government, or industry by offering an integrated, inter- disciplinary curriculum that emphasizes basic or clinical & translational science training in one of three major substantive areas: (1) gastrointestinal mucosal biology & signaling, (2) gut microbiome, immunology & genetics, and (3) hepatobiliary disorders. UMB entities represented by faculty mentors with robust federal funding portfolios cut across schools, departments, and organized research centers and institutes to include the Schools of Medicine (Departments of Medicine, Pediatrics, Surgery, Epidemiology & Public Health, Microbiology & Immunology, Biochemistry & Molecular Biology) and Pharmacy (Department of Pharmaceutical Sciences), the Center for Vaccine Development & Global Health, and the Institute for Genome Sciences. Comprehensive training opportunities allow predoctoral trainees to obtain PhD or MD/PhD degrees and postdoctoral trainees to earn MS, MPH or PhD degrees. Under the supervision of expert mentors, this training program is designed to enable trainees to develop hypotheses, design and perform basic or clinical research to test these hypotheses, become expert in at least one substantive area relevant to digestive or liver diseases, develop oral and written presentation skills, master the principles of responsible conduct of research, and prepare for transition to careers focused on the study of the biology and pathobiology of the GI tract and hepatobiliary system. Basic and clinical & translational science training in three focus areas (GI Mucosal Biology & Signaling; Gut Microbiome, Immunology & Genetics; Hepatobiliary Disorders), is directed by accomplished, highly productive experienced mentors who interact both within and amongst research tracks. Since its inception in 2005, this T32 program has been highly successful; all training slots were consistently filled, trainee retention was 100%, and productivity as measured by publications, awarding of advanced degrees, and career outcomes has been exceptional. All predoctoral trainees who completed training qualified for the PhD degree and nearly all MD postdoctoral trainees either have or will be awarded advanced degrees (MS, MPH, or PhD). This T32 program remains extraordinarily diverse, fulfilling a societal need to redress underrepresentation in biomedical research and academia; two-thirds of our trainees are women and one-fifth are Latino or African American. Former trainees obtained academic faculty appointments or perform research for federal agencies (NIH and FDA) or industry, competed successfully for federal funding, and attained leadership positions in academia. Notably, by attracting talented trainees and investigators from other disciplines to basic and patient-centered digestive diseases and liver research, this T32 program adds great value to the UMB clinical, educational and scientific community.