New imaging techniques
New imaging techniques
批准号:
7734998
负责人:
HAN WEN
金额:
$158.72万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AreaAtherosclerosisCardiacCardiovascular systemCarotid ArteriesClinicalCollaborationsDataDiagnosticFamily suidaeGoalsHumanImageImaging TechniquesIschemiaMagnetic Resonance ImagingMicroscopicModelingPatientsPatternPerfusionPurposeStructureSus scrofaTechniquesTestingTimeWorkbasebiological researchcardiographyimprovedinterestvalidation studies
中文摘要
作为心脏功能磁共振成像工作的继续,我们与两个临床小组合作进行了患者测试,比较了位移编码的MRI评估(Dense)和回声心动图评估,结果显示新的MRI评估显著提高了检测异常功能的敏感性。
在一个相关的项目中,我们开始将心脏灌注和功能成像结合起来,并在猪缺血模型上获得了第一个结果。
使用类似的技术,我们在人类身上完成了第一项关于颈动脉区域顺应性模式的验证性研究。这是研究区域顺应性分布与动脉粥样硬化之间关系的基础。
在X射线成像领域,我们建造了一台台式扫描仪,采用了一种将图像对比度与微观结构相关联的新技术,并获得了演示这一原理的第一批数据。
英文摘要
As a continuation of the work in MR imaging of cardiac function, we performed patient tests comparing displacement-encoded MRI assessment (DENSE) with echo-cardiography assessment in collaboration with two clinical groups, and showed that the new MRI assessment significantly improves the sensitivity in detecting abnormal function.
In a related project we began to combine cardiac perfusion and function imaging and obtained first results in a pig ischemia model.
Using a similar technique, we finished the first validation study in humans on the carotid artery regional compliance pattern. This serves as the basis to look at the relationship between regional compliance distribution and atherosclerosis.
In the area of x-ray imaging, we constructed a benchtop scanner of a new technique that relates the image contrast to microscopic structures, and obtained first data demonstrating the principle.
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The potential for Hall effect breast imaging.
霍尔效应乳腺成像的潜力。
DOI:
10.3233/bd-1998-103-418
发表时间:
1998
期刊:
Breast disease
影响因子:
--
作者:
[Wen,H, Balaban,RS]
通讯作者:
Balaban,RS
Effect of muscle action and metabolic strain on oxidative metabolic responses in human skeletal muscle.
肌肉活动和代谢应变对人体骨骼肌氧化代谢反应的影响。
DOI:
10.1152/jappl.1999.87.5.1768
发表时间:
1999
期刊:
Journal of applied physiology (Bethesda, Md. : 1985)
影响因子:
--
作者:
[Combs,CA, Aletras,AH, Balaban,RS]
通讯作者:
Balaban,RS
DOI:
10.1002/mrm.21621
发表时间:
2008-07
期刊:
MAGNETIC RESONANCE IN MEDICINE
影响因子:
3.3
作者:
[Lin, Alexander P., Bennett, Eric, Wisk, Lauren E., Gharib, Morteza, Fraser, Scott E., Wen, Han]
通讯作者:
Wen, Han
Shielding of piezoelectric ultrasonic probes in Hall effect imaging.
霍尔效应成像中压电超声探头的屏蔽。
DOI:
10.1177/016173469802000305
发表时间:
1998
期刊:
Ultrasonic imaging
影响因子:
2.3
作者:
[Wen,H, Bennett,E, Wiesler,DG]
通讯作者:
Wiesler,DG
Detection of myocardial capillary orientation with intravascular iron-oxide nanoparticles in spin-echo MRI.
在旋转回声 MRI 中用血管内氧化铁纳米颗粒检测心肌毛细血管方向。
DOI:
10.1002/mrm.20827
发表时间:
2006
期刊:
Magnetic resonance in medicine
影响因子:
3.3
作者:
[Vignaud,Alexandre, Rodriguez,Ignacio, Ennis,DanielB, DeSilva,Ranil, Kellman,Peter, Taylor,Joni, Bennett,Eric, Wen,Han]
通讯作者:
Wen,Han
共 10 条
New Non-invasive Imaging Methods For Biomedical Applicat
-
批准号:6675582
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:HAN WEN
-
依托单位:
MRI of cardiac function and myocardial tissue properties
-
批准号:6967052
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:HAN WEN
-
依托单位:
Advanced x-ray imaging and computed tomography
-
批准号:8746579
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项目类别:
-
资助金额:$113.72万
-
财政年份:--
-
负责人:HAN WEN
-
依托单位:
Compact x-ray nanoscopy
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批准号:8746693
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项目类别:
-
资助金额:$5.81万
-
财政年份:--
-
负责人:HAN WEN
-
依托单位:
Advanced x-ray imaging and computed tomography
-
批准号:8557937
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项目类别:
-
资助金额:$85.29万
-
财政年份:--
-
负责人:HAN WEN
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依托单位:
Compact x-ray nanoscopy
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批准号:8939894
-
项目类别:
-
资助金额:$2.0万
-
财政年份:--
-
负责人:HAN WEN
-
依托单位:
X-Ray Phase Contrast Imaging Concepts and Systems
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批准号:8939788
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项目类别:
-
资助金额:$99.82万
-
财政年份:--
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负责人:HAN WEN
-
依托单位:
Ultra-high resolution CT and quantitative CT development and clinical applications
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批准号:10929148
-
项目类别:
-
资助金额:$166.48万
-
财政年份:--
-
负责人:HAN WEN
-
依托单位:
New Non-invasive IMAGING methods for biomedical applications
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批准号:6432713
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:HAN WEN
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依托单位:
New Non-invasive Imaging Methods For Biomedical Applicat
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批准号:6541712
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:HAN WEN
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依托单位:
Mouse coronary micro computed tomography
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批准号:8558076
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项目类别:
-
资助金额:$8.53万
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财政年份:--
-
负责人:HAN WEN
-
依托单位:
New imaging techniques
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批准号:7969074
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项目类别:
-
资助金额:$186.33万
-
财政年份:--
-
负责人:HAN WEN
-
依托单位:
Technical development of x-ray phase contrast imaging
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批准号:8746715
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项目类别:
-
资助金额:$56.29万
-
财政年份:--
-
负责人:HAN WEN
-
依托单位:
Ultra-high resolution CT and quantitative CT development and clinical applications
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批准号:10706172
-
项目类别:
-
资助金额:$127.05万
-
财政年份:--
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负责人:HAN WEN
-
依托单位:
X-ray micro tomography of pathology tissue samples
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批准号:10253867
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项目类别:
-
资助金额:$51.77万
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财政年份:--
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负责人:HAN WEN
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依托单位:
X-Ray Novel Imaging Optics and Methods
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批准号:10253812
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项目类别:
-
资助金额:$17.26万
-
财政年份:--
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负责人:HAN WEN
-
依托单位:
Magnetic resonance imaging of cardiacvascular function
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批准号:7158554
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:HAN WEN
-
依托单位:
New imaging techniques
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批准号:7594416
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项目类别:
-
资助金额:$272.63万
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财政年份:--
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负责人:HAN WEN
-
依托单位:
X-ray micro tomography of pathology tissue samples
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批准号:10929149
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项目类别:
-
资助金额:$41.62万
-
财政年份:--
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负责人:HAN WEN
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依托单位:
Mouse coronary micro computed tomography
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批准号:8344932
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项目类别:
-
资助金额:$29.38万
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财政年份:--
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负责人:HAN WEN
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依托单位:
海外基金