Training in Bioenergetics, Oxidative Stress and Metabolic Syndrome
Training in Bioenergetics, Oxidative Stress and Metabolic Syndrome
批准号:
8667109
负责人:
John J Lemasters
金额:
$10.16万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-05-01 至 2019-04-30
中文摘要
这是一个旨在培养生物能量学研究的博士前和博士后科学家的计划,
氧化应激和代谢综合征(BOSMS)。它的目标是培养有才华的年轻人
在基础研究和临床研究领域,教他们设计和进行成功的
研究项目,并提供了一个坚实的背景,在道德和科学研究的方法。的
我们奖学金的目的是增加对代谢综合征,生物能量学和
氧化应激在南卡罗来纳州医科大学(MUSC),并训练个人成为
代谢综合征及相关疾病领域的独立研究者。将挑选学员
从众多候选人中脱颖而出将特别努力查明少数族裔申请人。BOSMS
该计划将分别为博士前和博士后提供长达三年和两年的支持
fellowsworking工作with a large大group组of talented有才华的faculty教师mentors导师.研究项目集中在以下领域:
生物能量学和氧化应激,因为它们涉及代谢综合征的各个方面,包括
胰岛素抵抗、糖尿病、肥胖症、血脂异常、肝脂肪变性、炎症和随后的组织
损伤每周与受训人员举行会议,使他们能够向研究界介绍自己的材料。
此外,学员还必须在部门内部研讨会上介绍他们的研究成果,
小组会议,并向国家会议提交摘要。博士预科学生将通过
研究生学院,并遵循生物医学科学博士学位的学习课程。接到
在细胞,分子和有机体生物学的基本培训,博士前学员将参加研究生
生物能量学和氧化应激课程,特别是与代谢综合征有关的课程。所有学员将
参加“负责任的研究行为”,“临床研究方法”和“统计”课程
生物医学研究方法》。学员还将有机会参加研究生水平的课程,
在MUSC提供各种研究课题,以提高他们的培训经验。指导委员会
将协助项目主任招聘和选择受训人员,批准研究和教学
计划,将受训人员分配到研究培训学院,并监测方案活动。内部和
外部咨询委员会将对培训计划进行额外评估,并向
指导委员会和方案主任。研究培训学院是成立的研究人员,
目前NIH或其他校外资金,并有经验的导师。教师有不同的兴趣,
允许多个候选人在培训计划中找到合适的导师。其他临床医生-
科学家导师将通过讨论
research.大量的研究资源MUSC和临床资源为
培养年轻的研究人员,他们将成为代谢综合征领域的未来学者。
英文摘要
This is a program designed to train pre- and post-doctoral scientists in research on Bioenergetics,
Oxidative Stress and Metabolic Syndrome(s) (BOSMS). Its goals are to nurture talented young individuals
in the areas of basic research and clinical investigation, teach them the design and conduct of successful
research projects, and provide a solid background in the ethics and methods of scientific research. The
objective of our fellowships is to increase the focus of research on metabolic syndrome, bioenergetics and
oxidative stress within the Medical University of South Carolina (MUSC) and to train individuals to become
independent investigators in the area of metabolic syndrome and related diseases. Trainees will be selected
from a broad group of candidates. Special efforts will be made to identify minority applicants. The BOSMS
program will provide up to three and two years of support, respectively, for predoctoral and postdoctoral
fellowsworking with a large group of talented faculty mentors. Research projects are concentrated in the areas
of bioenergetics and oxidative stress as they relate to various aspects of the metabolic syndrome, including
insulin resistance, diabetes, obesity, dyslipidemia, hepatic steatosis, inflammation and consequent tissue
injury. Weekly conferences with the trainees allow them to present their material to the research community.
Additionally, trainees are required to present their research at in-house departmental seminars and interest
group meetings and to submit abstracts to national meetings. Predoctoral students will matriculate through the
College of Graduate Studies and follow the course of study for the PhD in Biomedical Sciences. After receiving
basic training in cell, molecular and organismal biology, predoctoral trainees will participate in graduate
courses on bioenergetics and oxidative stress especially in relation to the metabolic syndrome. All trainees will
attend courses on "Responsible Conduct of Research", "Methods in Clinical Research", and "Statistical
Methods in Biomedical Research". Trainees will also have the opportunity to attend graduate level courses on
a variety of research topics available at MUSC to enhance their training experience. The Steering Committee
will assist the Program Director in recruitment and selection of trainees, approval of research and didactic
plans, assignment of trainees to Research Training Faculty, and monitoring of program activities. Internal and
External Advisory Committees will provide additional evaluation of the training program and feedback to the
Steering Committee and Program Director. Research Training Faculty are established investigators with
current NIH or other extramural funding and are experienced mentors. The faculty has diverse interests,
allowing multiple candidates to find appropriate mentors within the training program. Additional Clinician-
Scientist mentors will provide guidance to trainees through discussion of the clinical dimensions of the
research. The large number of research resources MUSC and clinical resources offer a rich environment for
the training of young investigators who will become future academicians in the area of metabolic syndrome.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Cell and Molecular Imaging Core
-
批准号:10460363
-
项目类别:
-
资助金额:$19.63万
-
财政年份:2021
-
负责人:John J Lemasters
-
依托单位:
Mechanisms of Mitochondrial Iron Uptake: New Therapeutic Targets in Hepatotoxicity
-
批准号:10210670
-
项目类别:
-
资助金额:$45.32万
-
财政年份:2021
-
负责人:John J Lemasters
-
依托单位:
Mechanisms of Mitochondrial Iron Uptake: New Therapeutic Targets in Hepatotoxicity
-
批准号:10349589
-
项目类别:
-
资助金额:$45.58万
-
财政年份:2021
-
负责人:John J Lemasters
-
依托单位:
Cell and Molecular Imaging Core
-
批准号:10674964
-
项目类别:
-
资助金额:$19.63万
-
财政年份:2021
-
负责人:John J Lemasters
-
依托单位:
Mechanisms of Mitochondrial Iron Uptake: New Therapeutic Targets in Hepatotoxicity
-
批准号:10597049
-
项目类别:
-
资助金额:$45.62万
-
财政年份:2021
-
负责人:John J Lemasters
-
依托单位:
Advanced Imaging Core
-
批准号:10608981
-
项目类别:
-
资助金额:$21.01万
-
财政年份:2020
-
负责人:John J Lemasters
-
依托单位:
Advanced Imaging Core
-
批准号:10586110
-
项目类别:
-
资助金额:$14.05万
-
财政年份:2020
-
负责人:John J Lemasters
-
依托单位:
Advanced Imaging Core
-
批准号:10395945
-
项目类别:
-
资助金额:$21.01万
-
财政年份:2020
-
负责人:John J Lemasters
-
依托单位:
Advanced Imaging Core
-
批准号:10337321
-
项目类别:
-
资助金额:$21.01万
-
财政年份:2020
-
负责人:John J Lemasters
-
依托单位:
Mitochondrial depolarization, mitophagy, and mitochondrial DAMPs in ALD
-
批准号:10155373
-
项目类别:
-
资助金额:$33.64万
-
财政年份:2018
-
负责人:John J Lemasters
-
依托单位:
Mitochondrial depolarization, mitophagy, and mitochondrial DAMPs in ALD
-
批准号:9920650
-
项目类别:
-
资助金额:$33.64万
-
财政年份:2018
-
负责人:John J Lemasters
-
依托单位:
Mitochondrial depolarization, mitophagy, and mitochondrial DAMPs in ALD
-
批准号:10736591
-
项目类别:
-
资助金额:$53.9万
-
财政年份:2018
-
负责人:John J Lemasters
-
依托单位:
Mitochondrial depolarization, mitophagy, and mitochondrial DAMPs in ALD
-
批准号:10398017
-
项目类别:
-
资助金额:$33.64万
-
财政年份:2018
-
负责人:John J Lemasters
-
依托单位:
Confocal/Multiphoton Microscope Upgrade
-
批准号:8826419
-
项目类别:
-
资助金额:$57.05万
-
财政年份:2015
-
负责人:John J Lemasters
-
依托单位:
VDAC in Ethanol and Aldehyde-Induced Mitochondrial Dysfunction
-
批准号:8928024
-
项目类别:
-
资助金额:$32.63万
-
财政年份:2014
-
负责人:John J Lemasters
-
依托单位:
VDAC in Ethanol and Aldehyde-Induced Mitochondrial Dysfunction
-
批准号:8761184
-
项目类别:
-
资助金额:$33.64万
-
财政年份:2014
-
负责人:John J Lemasters
-
依托单位:
VDAC in Ethanol and Aldehyde-Induced Mitochondrial Dysfunction
-
批准号:9302602
-
项目类别:
-
资助金额:$33.64万
-
财政年份:2014
-
负责人:John J Lemasters
-
依托单位:
Cell & Molecular Imaging Core
-
批准号:10005397
-
项目类别:
-
资助金额:$15.32万
-
财政年份:2011
-
负责人:John J Lemasters
-
依托单位:
Liver Preservation for Transplantation
-
批准号:8013388
-
项目类别:
-
资助金额:$6.65万
-
财政年份:2010
-
负责人:John J Lemasters
-
依托单位:
Research Training in Bioenergetics, Oxidative Stress & Metabolic Syndromes
-
批准号:7800934
-
项目类别:
-
资助金额:$19.08万
-
财政年份:2009
-
负责人:John J Lemasters
-
依托单位:
海外基金