Pharmacological Sciences Training Grant

 描述(由申请人提供)：本申请是对圣路易斯大学医学院药理学培训计划26年多来持续支持的请求。我们为六名优秀的博士前学生寻求资金支持，他们将攻读博士学位，重点研究细胞通讯和疾病。这是一项基础广泛、多学科的努力，涉及圣路易斯大学医学院五个系的21名教职员工。这些科室包括：药理学和生理学；生物化学和分子生物学；化学；内科；耳鼻喉科和世界卫生与医学中心。学生将从成功完成基础生物医学科学一年核心计划的候选人、直接进入高等学位的学生或完成医学院头两年课程的医学博士/博士学生中挑选。我们设计了一门课程，提供深入的药理学培训，无论学生的背景如何。在第一年的学习中，所有传统的博士生都要参加生物医学科学跨学科核心研究生项目。该计划旨在为学生提供基础生物医学科学各方面的坚实基础，以及探索不同研究机会的自由。课程包括讲座、小组讨论和研讨会。参加药理学培训计划的学生参加高级药理学、期刊俱乐部和研讨会。这一培训计划的关键是将定量药理学方法、化学生物学工具的应用和药物发现技术整合到正式培训计划中。我们利用制药行业的几位关键同事来加强这部分培训计划。所有博士候选人的后续培训将集中于在药理学培训学院的一名或多名成员的指导下，发展特定研究领域的研究和教学能力。参与这一计划的导师和实验室都有能力提供最先进的研究培训。此外，还提供先进技术的核心和共用设施，以加强参与候选人的研究培训。由T32药理科学培训助学金资助的学生有机会参加一系列独特的丰富活动。这一培训方案的总体目标是为个人提供在药理学领域取得高度能力的机会，从而为他们的教学和研究生涯做好准备。

 DESCRIPTION (provided by applicant): This application is a request for the 26+ years of continuous support for the Training Program in the Pharmacological Sciences of the Saint Louis University School of Medicine. We seek financial support for six outstanding predoctoral students who will be working for a Ph.D. degree with research emphasis on cellular communication and disease. This is a broadly based, multidisciplinary effort, which involves 21 faculty members from five departments in the Saint Louis University School of Medicine. These departments include: Pharmacological and Physiological Science; Biochemistry and Molecular Biology; Chemistry; Internal Medicine; Otolaryngology and the Center for World Health and Medicine. Students will be selected from candidates who have successfully completed the one year Core Program in Basic Biomedical Science, directly enter with advanced degrees, or M.D./Ph.D. students who have completed the first two years of medical school. We have designed a curriculum that provides in-depth training in Pharmacological Science regardless of the student's background. During the first year of study, all traditional Ph.D. students enroll in the interdisciplinary Core Graduate Program in Biomedical Sciences. This program is designed to provide students with a strong foundation in all aspects of basic biomedical science and the freedom to explore diverse research opportunities. The curriculum combines lectures, small group discussion and seminars. Students entering the Pharmacological Sciences Training Program take advanced pharmacology, journal clubs and seminars. Key to this training program is integration of quantitative pharmacological approaches, application of chemical biology tools, and drug discovery techniques into the formal training program. We utilize several key colleagues from the pharmaceutical industry to enhance this portion of the training program. Subsequent training for all Ph.D. candidates will concentrate on the development of research and teaching competence in a specific area of inquiry under the mentorship of one or more members of the Pharmacological Sciences Training Faculty. The mentors and laboratories participating in this program are well equipped to provide state-of-the-art research training. In addition, core and shared facilities for advanced technologies are available for enhancement of the research training of the participating candidates. Students supported by the T32 Pharmacological Sciences Training Grant have access to a range of unique enrichment activities. The overall objectives of this training program are to provide individuals with the opportunity to achieve a high degree of competence in the area of pharmacological sciences thus preparing them for teaching and research careers.