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Regulation of nucleocytoplasmic transport; role in health and disease

Regulation of nucleocytoplasmic transport; role in health and disease
核细胞质运输的调节;
批准号:
nhmrc : 1002486
负责人:
Prof David Jans
金额:
$54.88万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2016-12-31

项目摘要

项目成果

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中文摘要
翻译
进出细胞核的运输是复杂生物体(如哺乳动物)细胞功能的核心。本研究计划旨在提高对核转运及其在医学相关病毒感染、癌症和正常细胞生长/发育背景下的调控的理解。它将有助于开发新的抗病毒疗法/疫苗、癌症药物递送策略以及了解男性不育的原因。
英文摘要
Transport into and out of the nucleus is central to the function of the cells from complex organisms such as mammals. This research program aims to improve understanding of nuclear transport and its regulation in the context of infection by medically relevant viruses, as well as in the context of cancer, and normal cell growth/development. It will contribute to developing new anti-viral therapeutics/vaccines, drug delivery strategies for cancer, and understanding causes of male infertility.
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Nuclear transport in stress
  • 批准号:
    DP190101966
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $37.21万
  • 财政年份:
    2019
  • 负责人:
    Prof David Jans
  • 依托单位:
Nuclear Transport in Health and Disease; Towards Therapeutics
  • 批准号:
    nhmrc : GNT1103050
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $85.2万
  • 财政年份:
    2016
  • 负责人:
    Prof David Jans
  • 依托单位:
Epigenetic regulation by PKC-theta in human breast cancer stem cells.
  • 批准号:
    nhmrc : GNT1105409
  • 项目类别:
    Project Grants
  • 资助金额:
    $81.81万
  • 财政年份:
    2016
  • 负责人:
    Prof David Jans
  • 依托单位:
Nuclear Transport in Health and Disease; Towards Therapeutics
  • 批准号:
    nhmrc : 1103050
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $58.74万
  • 财政年份:
    2016
  • 负责人:
    Prof David Jans
  • 依托单位:
国内基金
海外基金
核孔蛋白NUP62调控开花时间的分子机制
  • 批准号:
    31970730
  • 项目类别:
    面上项目
  • 资助金额:
    58.0万元
  • 批准年份:
    2019
  • 负责人:
    胡红红
  • 依托单位: