课题基金 / 基金详情

Understanding how membrane trafficking controls the levels of Alzheimer's disease causing A? peptides

Understanding how membrane trafficking controls the levels of Alzheimer's disease causing A? peptides
了解膜运输如何控制导致阿尔茨海默病的 A 水平?
批准号:
nhmrc : 1042082
负责人:
A/Pr Brett Collins
金额:
$31.93万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2016-12-31

项目摘要

项目成果

A/Pr Brett Collins的其他基金

相似基金

相关文献

中文摘要
翻译
阿尔茨海默病是一种进行性神经系统疾病,是导致痴呆症的最常见原因。目前还没有有效的治疗方法。这种有毒的淀粉样肽是疾病病理的核心,来自阿尔茨海默氏症淀粉样前体蛋白(APP)的分解。在这个项目中,我们将研究APP与控制其在细胞中的位置和随后的降解的分子机制之间的相互作用。
英文摘要
Alzheimer’s disease is a progressive neurological disorder and is the most common cause of dementia. No effective treatments are currently available. The toxic amyloid peptide is central to disease pathology and is derived from breakdown of the Alzheimer’s amyloid precursor protein (APP). In this project we will examine the interactions between APP and the molecular machinery that controls its location in the cell and subsequent degradation.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Peripheral Membrane Proteins In Health And Disease
  • 批准号:
    nhmrc : GNT1136021
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $64.02万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Brett Collins
  • 依托单位:
Regulation of glutamate receptor trafficking by the calcium- and lipid-binding protein, copine-6
  • 批准号:
    nhmrc : 1138452
  • 项目类别:
    Project Grants
  • 资助金额:
    $37.1万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Brett Collins
  • 依托单位:
Regulation of glutamate receptor trafficking by the calcium- and lipid-binding protein, copine-6
  • 批准号:
    nhmrc : GNT1138452
  • 项目类别:
    Project Grants
  • 资助金额:
    $54.87万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Brett Collins
  • 依托单位:
Unveiling the origin of Munc18-1 and alpha-synuclein co-aggregation at nanoscale
  • 批准号:
    nhmrc : GNT1139316
  • 项目类别:
    Project Grants
  • 资助金额:
    $62.0万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Brett Collins
  • 依托单位:
海外基金