New Reactions and Strategies in Synthesis

该项目侧重于开发新方法和新策略，以便在实验室中轻松构建复杂分子。这项研究具有实践性，因此，可以想象，这项工作的创新可能会在工业上得到应用，比如精细化学或制药产品的合成。一些新的转化，形成碳-碳，碳-氧和碳-氮键与绝对立体化学控制将被研究。分子复杂性将以可预测的方式迅速发展。转化后的复杂产物很有希望成为化学合成中有用的新构件，在科学和商业企业的许多不同领域都有潜在的应用。有了这个奖项，有机和大分子化学项目支持了哈佛大学化学和化学生物系的安德鲁·g·迈尔斯博士的研究。Myers博士将专注于开发可应用于复杂综合问题的综合方法。这项工作的广泛影响是在制药、农业和材料化学领域。此外，该项目为研究生的培养提供了良好的环境。

The project focuses on the development of new methods and new strategies for the facile construction of complex molecules in the laboratory. The research is by design of practical nature, thus, it is conceivable that innovations from the work might find industrial applications, such as in fine-chemical or pharmaceutical product synthesis. A number of new transformations that form carbon-carbon, carbon-oxygen, and carbon-nitrogen bonds with absolute stereo-chemical control will be investigated. Molecular complexity will be developed rapidly and in ways that are subject to prediction. The complex products of the transformations hold great promise to function as useful new building blocks in chemical synthesis, with potential applications in many different areas of scientific and commercial enterprise.With this award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. Andrew G. Myers in the Department of Chemistry and Chemical Biology at Harvard University. Dr. Myers will focus his work on developing synthetic methodology that can be applied to complex synthetic problems. The broader impact of the work is in the areas of pharmaceutical, agricultural and materials chemistry. Further, the project presents an excellent setting for the training of graduate students.