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Transcriptional and epigenetic regulation of terminal lymphocyte differentiation and alterations of the same that lead to leukemia.

Transcriptional and epigenetic regulation of terminal lymphocyte differentiation and alterations of the same that lead to leukemia.
终末淋巴细胞分化的转录和表观遗传调控及其导致白血病的改变。
批准号:
FT0992164
负责人:
Prof Axel Kallies
金额:
$42.43万
依托单位国家:
澳大利亚
项目类别:
ARC Future Fellowships
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2013-12-31

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中文摘要
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英文摘要
In the developed world infection diseases are the number three killer behind heart disease and cancer, and huge financial effort is put into treatment and prevention. Despite this, results have often been disappointing. One cause of these poor outcomes is the lack of knowledge of how effective immune responses are generated. This project aims to better understand the processes that control the generation of protective lymphocytes. It will deliver information that may enable a more targeted approach to vaccine-development and treatments of infections. As defective differentiation can also be a cause of leukemia it may also lead to targets of cancer treatment.
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Differentiation of effector and tissue regulatory T cells
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    DP210102705
  • 项目类别:
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  • 财政年份:
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  • 负责人:
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Transcriptional and metabolic regulation of effector and memory lymphocyte differentiation
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  • 负责人:
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国内基金
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  • 项目类别:
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  • 资助金额:
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