Academic project of oncogenic factors in malignant tumors and the related diseases in northeast China
Academic project of oncogenic factors in malignant tumors and the related diseases in northeast China
批准号:
19406007
负责人:
HASUI Kazuhisa
金额:
$10.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2010
中文摘要
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英文摘要
This study examined many cases of nasopharyngeal lymphomas frequently seen in northeast China, elucidating neoplastic expansion of Epstein-Barr virus (EBV) latent infection, complication of minute EBV-not-associated squamous cell carcinoma in EBV-associated NK/T-cell lymphomas, peculiar necrosis of autophagic cell death, lymphoma cells' antioxidant response suggesting point mutations induced by environmental factors before its occurrence, and peculiar symbiotic dendritic cells and developed immunohistochemical methods of malignant tumor diagnosis by detecting a nature of tissue stem cells, analysis for autophagy and its cell death, and analysis for oxidation in DNA.
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Possible role for external environmental stimuli in nasopharyngeal NK/T-cell lymphomas in the northeast of China with EBV infection-related autophagic cell death.
外部环境刺激在中国东北地区鼻咽 NK/T 细胞淋巴瘤中与 EBV 感染相关的自噬细胞死亡中的可能作用。
DOI:
--
发表时间:
2009
期刊:
J Clin Exp Hematop. 49(2)
影响因子:
--
作者:
[Wang J, Hasui K, Jia X, Matsuyama T, Eizuru Y.]
通讯作者:
Eizuru Y.
Possible role for external environmental stimuli in nasopharyngeal NK/T-cell lymphomas in the northeast of China with EBV infection-related autophagic cell death : a pathoepidemiological analysis
外部环境刺激在中国东北地区鼻咽NK/T细胞淋巴瘤中EB病毒感染相关自噬性细胞死亡中的可能作用:病理流行病学分析
DOI:
--
发表时间:
2009
期刊:
J Clin Exp Hematopath 49(2)
影响因子:
--
作者:
[Wang J, Hasui K, Jia XS, Matsuyama T, Eizuru Y.]
通讯作者:
Eizuru Y.
Association of High Proliferation in Adult T-cell Leukemia Cells with Apoptosis, and Expression of p53 Protein in Acute Type ATL.
成人 T 细胞白血病细胞高增殖与细胞凋亡的关联以及急性型 ATL 中 p53 蛋白的表达。
DOI:
--
发表时间:
2008
期刊:
Journal of Clinical and Experimental Hemato pathology 48
影响因子:
--
作者:
[Jia Wang, Kazuhisa Hasui, Atae Utsunomiya, xinshan Jia, Takami Matsuyama, Fusayoshi Murata.]
通讯作者:
Fusayoshi Murata.
鼻咽頭リンパ腫における活性酸素種による損傷の免疫組織化学的解析
鼻咽淋巴瘤活性氧损伤的免疫组织化学分析
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[蓮井和久, 賈心善, 田代幸恵, 青笹克之, 佐藤榮一]
通讯作者:
佐藤榮一
EBV感染下の自己貪食・自己貪食細胞死は鼻咽頭リンパ腫の特異な壊死を特徴づけている(免疫組織化学的自己貪食機能解析の試み)
EBV感染下的自噬和自噬细胞死亡是鼻咽淋巴瘤特有的坏死特征(尝试通过免疫组化分析自噬功能)
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[蓮井和久, 王嘉, 賈心善, 松山隆美, 榮鶴義人]
通讯作者:
榮鶴義人
共 39 条
Academic research project on oncogenic factors in malignant tumors in the eastnorthern China
-
批准号:16406006
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.34万
-
财政年份:2004
-
负责人:HASUI Kazuhisa
-
依托单位:
Development of preditection method to prevent occurrence of adult T-cell leukemia/lymphoma (ATLL)
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批准号:13557017
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.77万
-
财政年份:2001
-
负责人:HASUI Kazuhisa
-
依托单位:
Academic research project on oncogenic factors in malignant lymphomas in the east-northern China
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批准号:13576003
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.82万
-
财政年份:2001
-
负责人:HASUI Kazuhisa
-
依托单位:
Oncogenic factors in Chinese gastric lymphoma
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批准号:11691216
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$2.43万
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财政年份:1999
-
负责人:HASUI Kazuhisa
-
依托单位:
A STUDY OF HTLV-1-RELATED DISEASES BY MEANS OF HIGHLY SENSITIVE HISTOCHEMISTRY
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批准号:10670166
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
-
财政年份:1998
-
负责人:HASUI Kazuhisa
-
依托单位:
In-situ-hybridization analysis of HTLV-1-related diseases, employing highly biotinylated probes synthesized by polymerase chain reaction
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批准号:05670176
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1993
-
负责人:HASUI Kazuhisa
-
依托单位:
海外基金