Research on the molecular mechanism underlying sudden cardiac deaths due to toxic substanses, ischemia and emotional stress
Research on the molecular mechanism underlying sudden cardiac deaths due to toxic substanses, ischemia and emotional stress
批准号:
20390193
负责人:
YOSHIDA Ken-ichi
金额:
$12.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
In rats, we found that ischemia induces Connexin-43 (Cx43) translocation to gap junction (GJ) and Phospholamaban (PLB) dephosphorylation, and reperfusion promotes spreading of Contraction Bands (CBs). We also found that anti-PLB antibody injection enlarges myocardial infarction through mPTP opening. In restrain of rats, Cx43 was translocated to the GJs, thereby reducing premature ventricular contractions and promoting GJ communication. As a result, lethal arrhythmias were suppressed.
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A death due to perirenal hematoma complicating extracorporeal shockwave lithotripsy
体外冲击波碎石术并发肾周血肿死亡一例
DOI:
--
发表时间:
2008
期刊:
J Forensic Sci 53(2)
影响因子:
--
作者:
[Uemura K, Takahashi S, Shintani-Ishida K, Nakajima M, Saka K, Yoshida K]
通讯作者:
Yoshida K
Restraint stress induces connexin-43 translocation via a-adr enoceptors in rat heart
束缚应激通过大鼠心脏中的 a-adr 受体诱导 connexin-43 易位
DOI:
--
发表时间:
2010
期刊:
Circ J.
影响因子:
--
作者:
[Unuma K, Shintani-lshida K, Yahagi N, Tsushima K, Shimosawa T, Ueyama T, Yoshida K.]
通讯作者:
Yoshida K.
An autopsy report on four sudden cardiac death cases by immobilization
4例因制动而导致心源性猝死的尸检报告
DOI:
--
发表时间:
2008
期刊:
Inter. Med. J. 15(4)
影响因子:
--
作者:
[Uemura K, Ueyama T, Shintani-Ishida K, Unuma K, Ken-ichi Y.]
通讯作者:
Ken-ichi Y.
タイのダイエット薬を服用中であった女性の突然死の1剖検例
一名服用泰国减肥药的妇女猝死尸检案
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[鵜沼香奈, 原田一樹, 坂幹樹, 中嶋信, 高橋香, 高橋麻衣子, 藤乗嗣泰, 吉田謙一]
通讯作者:
吉田謙一
Cardiac and vascular gene profiles in an animal model of takotsubo cardiomyopathy
takotsubo 心肌病动物模型中的心脏和血管基因谱
DOI:
--
发表时间:
2011
期刊:
Heart Vessels
影响因子:
1.5
作者:
[Ueyama T, Yamamoto Y, Ueda K, Kawabe T, Hano T, Ito T, Tsuruo Y, Ichinose M, Yoshida K]
通讯作者:
Yoshida K
共 29 条
Research on rational singularities and almost Gorenstein blow-up algebras
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批准号:16K05110
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.58万
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财政年份:2016
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负责人:YOSHIDA Ken-ichi
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依托单位:
Study on sudden cardiovascular death in animal model of sleep apnea syndrome
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批准号:23249038
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$31.87万
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财政年份:2011
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负责人:YOSHIDA Ken-ichi
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依托单位:
Metabolism of inositol stereoisomers in a thermophile,Geobacillus kaustophilusHTA426
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批准号:22310130
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2010
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负责人:YOSHIDA Ken-ichi
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依托单位:
Research of ring-invariants associated to powers of ideals
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批准号:22540047
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2010
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负责人:YOSHIDA Ken-ichi
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依托单位:
Research of multiplier ideals and tight closures from viewpoint of commutative algebra and computational algebra
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批准号:19340005
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.41万
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财政年份:2007
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负责人:YOSHIDA Ken-ichi
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依托单位:
Research on the contribution of oxidative stress to the pathogenesis of cardiovascular diseases associated with life-styles
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批准号:18390204
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.86万
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财政年份:2006
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负责人:YOSHIDA Ken-ichi
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依托单位:
Study into the Dynamism and Fluctuational Factors of Foreign Exchange Rates
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批准号:15530225
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.02万
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财政年份:2003
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负责人:YOSHIDA Ken-ichi
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依托单位:
Research on cell injury due to Carbon Monoxide and Nitric Oxide under ischemia or shock
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批准号:14370152
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.73万
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财政年份:2002
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负责人:YOSHIDA Ken-ichi
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依托单位:
On ring-theoretical properties of blow-up rings over singular points in positive characteristic
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批准号:14540020
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:2002
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负责人:YOSHIDA Ken-ichi
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依托单位:
Identification of new fatty acids associated with pathogenesis of ischemia and various types of intoxication and its application to a new diagnostic method
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批准号:12470107
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.54万
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财政年份:2000
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负责人:YOSHIDA Ken-ichi
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依托单位:
FORENSIC PATHOLOGICAL STUDY ON PROTEINS AND GENES INDUCED BY STRESS OR ISCHEMIA
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批准号:10470120
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$1.54万
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财政年份:1998
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负责人:YOSHIDA Ken-ichi
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依托单位:
On the roles of generalized linear CM modules in commutative ring theory
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批准号:09640025
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:1997
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负责人:YOSHIDA Ken-ichi
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依托单位:
Study on the involvement of platelet in sudden cardiac death
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批准号:02670259
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.47万
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财政年份:1990
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负责人:YOSHIDA Ken-ichi
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依托单位:
海外基金