Environmental and genetic risk factors for gallbladder cancer in Bolivian people
Environmental and genetic risk factors for gallbladder cancer in Bolivian people
批准号:
21590650
负责人:
YAMAMOTO Masaharu
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
我们测量了玻利维亚红辣椒中黄曲霉毒素的浓度,然后确定黄曲霉毒素污染的红辣椒消费是否是胆囊癌发展的原因。从1份样本中检测到黄曲霉毒素B1浓度为11.3 ppb。然而,几种红辣椒的浓度低于我们的分析方法的检测限。由于我们的研究结果表明,低水平,但长期暴露于黄曲霉毒素可能与胆囊癌的发展,进一步的研究,如调查的污染物的背景,是必要的。
英文摘要
We measured the concentrations of aflatoxins in Bolivian red chili pepper, and then determined whether aflatoxin-contaminated red chili pepper consumption is the cause of the development of gallbladder cancer. Aflatoxin B1 was detected at concentration of 11.3 ppb from 1 sample. However the concentrations of several red chili peppers were less than the detection limit of our analysis method. Since our findings suggest that the low-level but protracted exposure to aflatoxins may be associated with the development of gallbladder cancer, further studies, such as investigation of the background of contaminants, are needed.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mutagenicity and mutagens of the red chili pepper as gallbladder cancer risk factor in Chilean women
红辣椒的致突变性和致突变剂作为智利女性胆囊癌的危险因素
DOI:
--
发表时间:
2011
期刊:
Asian Pac J Cancer Prev
影响因子:
--
作者:
[Tsuchiya Y, Terao M, Okano K, Nakamura K, Oyama M, Ikegami K, Yamamoto M]
通讯作者:
Yamamoto M
Polimorfismo genetico relacionado al metabolismo de la aflatoxina y el riesgo de cancer vesicular en mujeres chilenas
智利女性黄曲霉毒素与癌症水泡的遗传关系多态性
DOI:
--
发表时间:
期刊:
Revista Gastroenterologia Latinoamericana
影响因子:
--
作者:
[Tsuchiya Y, Baez S, Calvo A, Pruyas M, Nakamura K, Kiyohara C, Endoh K, Asai T, Yamamoto M]
通讯作者:
Yamamoto M
Aflatoxin contamination of red chili pepper as a risk factor for gallbladder cancer in Chilean women
红辣椒中的黄曲霉毒素污染是智利女性胆囊癌的危险因素
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Tsuchiya Y, Serra I, Endoh K, Yamamoto M]
通讯作者:
Yamamoto M
International and Epidemiological Studies on the Causes of Gallbladder Cancer in Hungary
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批准号:15406025
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.0万
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财政年份:2003
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负责人:YAMAMOTO Masaharu
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依托单位:
Concentrations of Free Fatty Acids in Human Bile Juice Collected from Patients with Gallstones in Chile
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批准号:13670332
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2001
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负责人:YAMAMOTO Masaharu
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依托单位:
Analytical Studies on Extraction and Identification of Carcinogenic Substances from Chili Pepper in Chile
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批准号:11670339
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1999
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负责人:YAMAMOTO Masaharu
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依托单位:
Epidemiological Studies on Free Fatty Acid Concentrations in Human Gallbladder Bile from the Point of View of Antimutagencity
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批准号:08670387
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.6万
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财政年份:1996
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负责人:YAMAMOTO Masaharu
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依托单位:
Studies on the Etiology of Gallbladder Cancer in Chile
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批准号:07042003
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$8.06万
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财政年份:1995
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负责人:YAMAMOTO Masaharu
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依托单位:
Epidemiological Studies on Mutagenicity of Human Bile
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批准号:06670376
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1994
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负责人:YAMAMOTO Masaharu
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依托单位:
Epidemiological Studies on Biliary Tract Cancer in Niigata, Japan
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批准号:04670307
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1992
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负责人:YAMAMOTO Masaharu
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依托单位:
Causes of the Biliary Tract Cancer from the Point of View of Environmental Epidemiology
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批准号:01570286
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.09万
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财政年份:1989
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负责人:YAMAMOTO Masaharu
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依托单位:
フェノキシ系除草剤の発癌性に関する遺伝毒性学的研究
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批准号:62570227
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.9万
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财政年份:1987
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负责人:YAMAMOTO Masaharu
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依托单位:
海外基金