Translational Research for cobinational chemotherapy with tumor microcirculation promotional agent in patients with advanced non-small cell lung cancer
Translational Research for cobinational chemotherapy with tumor microcirculation promotional agent in patients with advanced non-small cell lung cancer
批准号:
23591133
负责人:
YASUDA Hiroyasu
金额:
$3.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
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英文摘要
Nitoroglycerin (NTG), nitric oxide donating agent (NDA), significantly reduced distribution of hypoxic area in solid cancer tissue in tumor bearing model mice. We made tumor bearing model mice with murine adenocarcinoma LLC cells and performed chemotherapy with them. Tumor growth curve was significantly inhibited in the group treated with pemetrexed and NTG compared with the group treated with pemetrexed alone.Multicenter-phase II trial of 3rd line chemotherapy with amrubicin with NTG patch in patients with stage IIIB and IV non-small cell lung cancer was performed in Kyoto Univ., Tohoku Univ., Shinshu Univ., and Juntendo Univ. Now the data analysis has been performed, and will be published.
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進行非小細胞肺癌に対するGTN+/-CBDCA・TXL化学療法の無作為化比較試験
GTN+/-CBDCA/TXL化疗治疗晚期非小细胞肺癌的随机对照试验
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
DOI:
10.1177/1753465810392264
发表时间:
2011-02
期刊:
Therapeutic Advances in Respiratory Disease
影响因子:
4.3
作者:
[Takahiko Sasaki;K. Nakayama;H. Yasuda;M. Yamaya]
通讯作者:
Takahiko Sasaki;K. Nakayama;H. Yasuda;M. Yamaya
Safty of erlotinib treatment in outpatients with previously treated non-small-cell lung cancer in Japan
日本既往接受过治疗的非小细胞肺癌门诊患者接受厄洛替尼治疗的安全性
DOI:
--
发表时间:
2011
期刊:
Int J Clin Oncol
影响因子:
3.3
作者:
[Nagai H, Tanaka S, Niimi M, et al.]
通讯作者:
et al.
Use of glucose solution for the alleviation of gemcitabine-induced vascular pain: a double blind randomized crossover study.
使用葡萄糖溶液缓解吉西他滨引起的血管疼痛:双盲随机交叉研究。
DOI:
10.1007/s00520-013-1901-9
发表时间:
2013
期刊:
Support Care Cancer
影响因子:
3.1
作者:
[Nagai H, Kitano T, Nishimura T, Yasuda H, Nakata K, Takashima S, Kanai M, Matsumoto S, Mori Y, Kakudo Y, Sato H, Yamaguchi T, Kameno K, Kim YH, Mishima M, Yanagihara K.]
通讯作者:
Yanagihara K.
Procaterol inhibits rhinovirus infection in primary cultures of human tracheal epithekial cells
丙卡特罗抑制人气管上皮细胞原代培养物中的鼻病毒感染
DOI:
--
发表时间:
2011
期刊:
Eur J Pharmacol
影响因子:
5
作者:
[Yamaya M, Nishimura H, Hatachi Y, et al.]
通讯作者:
et al.
共 9 条
Study on Design Method of River Plane Form
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批准号:24686057
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项目类别:Grant-in-Aid for Young Scientists (A)
-
资助金额:$5.32万
-
财政年份:2012
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负责人:YASUDA Hiroyasu
-
依托单位:
Development of numerical model for meandering process with new boundary fitting method based on the Cartesian coordinate system
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批准号:20760336
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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财政年份:2008
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负责人:YASUDA Hiroyasu
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依托单位:
The basic and clinical research regarding development of combinationalchemotherapy with nitric oxide donating drugs for non-small cell lung cancer
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批准号:19689018
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项目类别:Grant-in-Aid for Young Scientists (A)
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资助金额:$17.22万
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财政年份:2007
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负责人:YASUDA Hiroyasu
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依托单位:
海外基金