Study on analytical techniques of conformations for environmental biopolymers in dynamic equilibrium

提出了蛋白质三维结构比对的超二级结构编码方法，建立了蛋白质7494个亚基的构象编码数据库。使用这些编码的搜索方法提取了与自我识别相关的免疫因子的特征超二级结构(球形蛋白中的结构区域折叠成重复单元)，并将片段结构表示为简单的描述。此外，使用振动圆二色谱(VCD)确定手性化合物绝对构型的构象搜索技术被转移到一家公司。

Supersecondary structure code (SSC) for 3D structural alignment of proteins was proposed, and the database of conformational code for 7494 subunits of proteins was constructed. The search method using these codes extracted the characteristic supersecondary structures (the structural regions in globular proteins folded into repetitive units) of immune factors related to self-recognition, and the fragment structures were represented as the simple description. Further, the conformational search techniques for absolute configuration determination of chiral compounds using vibrational circular dichroism (VCD) spectroscopy were transferred to a company.