Biostatistics

生物统计学

• 批准号: 10411091
• 负责人: MANISHA DESAI
• 金额: $ 12.95万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-04 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10411091
• 关键词: Adoption; Basic Science; Biometry; Biostatistics Shared Resource; Budgets; Cancer Center Support Grant; Clinical; Clinical Sciences; Clinical Trials; Clinical Trials Design; Clinical effectiveness; Collaborations; Data; Development; Dose; Effectiveness; Feedback; Funding; Goals; Human Resources; Individual; Institutes; Malignant Neoplasms; Mentors; Methodology; Methods; Mining; Mission; Modernization; Monitor; Nature; Phase; Play; Population Sciences; Protocols documentation; Publications; Randomized; Reproducibility; Research; Research Design; Research Methodology; Research Personnel; Research Technics; Resources; Review Committee; Sample Size; Scientist; Statistical Data Interpretation; Statistical Methods; Techniques; Therapeutic; Training; Translational Research; base; biomedical informatics; data management; design; effectiveness research; improved; informatics shared resource; innovation; member; peer; programs; sound; synergism; translational study

PROJECT SUMMARY The Biostatistics Shared Resource (B-SR) personnel collaborate with SCI members in all seven programs and support all phases of research, from population and basic sciences through translational studies to clinical trials and effectiveness research. Capabilities are matched to the needs of SCI members, providing a full range of biostatistics and study design expertise, from standard techniques to innovative methods developed specifically to enhance the basic, translational, clinical, and population sciences research efforts. Since the last review and based on SCI member feedback, the former Biostatistics and Informatics Shared Resource was divided into two separate resources in 2017 (with EAB and NCI approval): (1) the B-SR and (2) the Biomedical Informatics Shared Resource (BI-SR). While the two resources continue to have synergy, the change has allowed for a deeper focus on each SR’s individual missions. The new BI-SR focuses on data organization, curation, management, and mining that supports the studies. The B-SR strengths are study design and results analysis, with emphasis on statistically sound methodology. The B-SR also plays a key role in the Protocol Review and Monitoring Committee and the Clinical Trials Scientific Review Committee. Members of all programs regularly use the B- SR, with the heaviest use coming from the Population Sciences and Cancer Therapeutics programs. The B-SR participated in 82 cancer-focused publications in the current funding period, 16 of them in high-impact publications. The annual budget of the B-SR is $261,592, yet the CCSG request is $149,916. Accordingly, the B-SR seeks 57% of its support from CCSG funds.

项目概要 生物统计共享资源 (B-SR) 人员与 SCI 成员在所有七个项目中进行合作， 支持所有阶段的研究，从人口和基础科学到转化研究再到临床试验 和有效性研究。能力与 SCI 会员的需求相匹配，提供全方位的 生物统计学和研究设计专业知识，从标准技术到专门开发的创新方法 加强基础、转化、临床和人口科学研究工作。自上次审查以来 根据SCI会员反馈，原生物统计与信息学共享资源分为两个 2017 年单独资源（经 EAB 和 NCI 批准）：(1) B-SR 和 (2) 生物医学信息共享 资源 (BI-SR)。虽然两种资源继续发挥协同作用，但这一变化使我们能够更加深入地关注 每个 SR 的个人任务。新的 BI-SR 侧重于数据组织、策划、管理和 支持研究的采矿。 B-SR 的优势是研究设计和结果分析，重点是 统计上合理的方法。 B-SR 在方案审查和监测中也发挥着关键作用 委员会和临床试验科学审查委员会。所有计划的成员都定期使用 B- SR，最常使用的是人口科学和癌症治疗项目。 B-SR 在当前资助期间参与了 82 篇以癌症为重点的出版物，其中 16 篇是高影响力的出版物 出版物。 B-SR 的年度预算为 261,592 美元，而 CCSG 的请求为 149,916 美元。据此， B-SR 寻求 CCSG 基金提供 57% 的支持。