Biostatistics

生物统计学

• 批准号: 10626974
• 负责人: MANISHA DESAI
• 金额: $ 12.95万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-04 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10626974
• 关键词: Adoption; Basic Science; Biometry; Biostatistics Shared Resource; Budgets; Cancer Center Support Grant; Clinical; Clinical Sciences; Clinical Trials; Clinical Trials Design; Clinical effectiveness; Collaborations; Data; Development; Dose; Effectiveness; Feedback; Funding; Goals; Human Resources; Individual; Malignant Neoplasms; Mentors; Methodology; Methods; Mining; Mission; Modernization; Monitor; Nature; Phase; Play; Population Sciences; Protocols documentation; Publications; Randomized; Reproducibility; Research; Research Design; Research Methodology; Research Personnel; Research Technics; Resources; Review Committee; Sample Size; Scientist; Statistical Data Interpretation; Statistical Methods; Techniques; Therapeutic; Training; Translational Research; biomedical informatics; data management; design; effectiveness research; improved; informatics shared resource; innovation; member; peer; programs; sound; synergism; translational study

PROJECT SUMMARY The Biostatistics Shared Resource (B-SR) personnel collaborate with SCI members in all seven programs and support all phases of research, from population and basic sciences through translational studies to clinical trials and effectiveness research. Capabilities are matched to the needs of SCI members, providing a full range of biostatistics and study design expertise, from standard techniques to innovative methods developed specifically to enhance the basic, translational, clinical, and population sciences research efforts. Since the last review and based on SCI member feedback, the former Biostatistics and Informatics Shared Resource was divided into two separate resources in 2017 (with EAB and NCI approval): (1) the B-SR and (2) the Biomedical Informatics Shared Resource (BI-SR). While the two resources continue to have synergy, the change has allowed for a deeper focus on each SR’s individual missions. The new BI-SR focuses on data organization, curation, management, and mining that supports the studies. The B-SR strengths are study design and results analysis, with emphasis on statistically sound methodology. The B-SR also plays a key role in the Protocol Review and Monitoring Committee and the Clinical Trials Scientific Review Committee. Members of all programs regularly use the B- SR, with the heaviest use coming from the Population Sciences and Cancer Therapeutics programs. The B-SR participated in 82 cancer-focused publications in the current funding period, 16 of them in high-impact publications. The annual budget of the B-SR is $261,592, yet the CCSG request is $149,916. Accordingly, the B-SR seeks 57% of its support from CCSG funds.

项目摘要 生物统计学共享资源（B-SR）人员在所有七个计划中与SCI成员合作， 支持研究的所有阶段，从人口和基础科学到转化研究到临床试验 和有效性研究。能力与SCI成员的需求相匹配，提供了全部的范围 生物统计学和研究设计专业知识，从标准技术到专门开发的创新方法 增强基本，翻译，临床和人口科学研究工作。自上次评论以来 根据SCI成员反馈，以前的生物统计学和信息学共享资源分为两个 2017年单独资源（获得EAB和NCI批准）：（1）B-SR和（2）共享的生物医学信息学 资源（BI-SR）。尽管这两个资源继续具有协同作用，但这种变化允许更深入的重点 在每个SR的个人任务上。新的BI-SR专注于数据组织，策展，管理和 支持研究的采矿。 B-SR优势是研究设计和结果分析，重点是 统计上有道理的方法论。 B-SR在协议审查和监视中也起着关键作用 委员会和临床试验科学审查委员会。所有程序的成员定期使用b- SR，最重的用途来自人口科学和癌症治疗计划。 B-SR 在当前的资助期间参加82个以癌症为中心的出版物，其中16个具有高影响力 出版物。 B-SR的年度预算为261,592美元，但CCSG请求为149,916美元。根据， B-SR从CCSG基金中寻求57％的支持。