Biostatistics

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PROJECT SUMMARY The Biostatistics Shared Resource (B-SR) personnel collaborate with SCI members in all seven programs and support all phases of research, from population and basic sciences through translational studies to clinical trials and effectiveness research. Capabilities are matched to the needs of SCI members, providing a full range of biostatistics and study design expertise, from standard techniques to innovative methods developed specifically to enhance the basic, translational, clinical, and population sciences research efforts. Since the last review and based on SCI member feedback, the former Biostatistics and Informatics Shared Resource was divided into two separate resources in 2017 (with EAB and NCI approval): (1) the B-SR and (2) the Biomedical Informatics Shared Resource (BI-SR). While the two resources continue to have synergy, the change has allowed for a deeper focus on each SR’s individual missions. The new BI-SR focuses on data organization, curation, management, and mining that supports the studies. The B-SR strengths are study design and results analysis, with emphasis on statistically sound methodology. The B-SR also plays a key role in the Protocol Review and Monitoring Committee and the Clinical Trials Scientific Review Committee. Members of all programs regularly use the B- SR, with the heaviest use coming from the Population Sciences and Cancer Therapeutics programs. The B-SR participated in 82 cancer-focused publications in the current funding period, 16 of them in high-impact publications. The annual budget of the B-SR is $261,592, yet the CCSG request is $149,916. Accordingly, the B-SR seeks 57% of its support from CCSG funds.