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EFFECT OF ETHANOL ON CEREBRAL BLOOD FLOW AND ENERGY METABOLISM IN THE RAT

EFFECT OF ETHANOL ON CEREBRAL BLOOD FLOW AND ENERGY METABOLISM IN THE RAT
乙醇对大鼠脑血流和能量代谢的影响
批准号：
3801934
负责人：
A C MCLAUGHLIN
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3801934
关键词：
alcoholic beverage consumption blood flow measurement brain metabolism diagnostic tests ethanol glucose metabolism laboratory rat oxygen consumption

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中文摘要
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英文摘要
We developed a new technique for measuring cortical cerebral blood flow in the rat, and combined it with measurements of arterial/venous differences for oxygen and glucose to calculate cerebral oxygen consumption and cerebral glucose consumption. The major advantage of this new technique is that it can be used in the unanesthetized, freely-moving, animal. Most of the previous studies on the effect of alcohol on cerebral blood flow and metabolic rate have been performed on restrained or anesthetized animals, where it is difficult to separate the effects of stress and anesthesia from the effects of alcohol.
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