STUDIES OF VISUAL PROCESSING & SMOOTH EYE MOVEMENTS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。我们的研究旨在确定与平稳追踪、眼球运动和凝视保持相关的视觉处理的神经基础。我们正在努力确定早期视觉体验与眼动系统、眼球对准和凝视保持之间的关系。视觉和眼球运动系统在出生时并不成熟。如果早期的视觉体验受到损伤或先天缺陷的影响，眼球运动障碍就会随之而来，从而影响清晰的视力。我们最近首次证明了MST皮质中的神经元具有适当的反应特性，在差异缩小中发挥作用。我们现在正在尝试针对眼睛对准、立体视觉和会聚发展的关键时期进行研究。我们还进行了研究，证明了主动和被动视觉运动的视觉潜伏期存在差异。这些发现表明，在视觉场景的主动扫描过程中，视觉潜伏期缩短，可能有助于眼跳时的视觉。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Our studies are directed at defining the neural substrate for visual processing related to smooth pursuit eye movements and gaze-holding. We are working to define the relationship between early visual experience and development of eye movement systems, eye alignment and gaze holding. The visual and oculomotor systems are not mature at birth. If early visual experience is compromised by injury or congenital defect, eye movement disorders can follow that can compromise clear vision. We have recently demonstrated for the first time that neurons in MST cortex have appropriate response properties to play a role in disparity vergence. We are now attempting studies that target the critical period in development of eye alignment, stereopsis and vergence. We have also conducted studies that demonstrate differences in visual latency for active and passive visual motion. These findings suggest that during active scanning of a visual scene that visual latencies are reduced, perhaps facilitating vision during saccades.