COLLAGEN ORIENTATION IN ARTICULAR CARTILAGE IMAGED WITH PS-OCT AND MPM
使用 PS-OCT 和 MPM 成像的关节软骨中的胶原蛋白方向
基本信息
- 批准号:7365644
- 负责人:
- 金额:$ 2.65万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2006
- 资助国家:美国
- 起止时间:2006-04-01 至 2007-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Polarization Sensitive Optical Coherence Tomography (PS-OCT) is being evaluated as a potential diagnostic tool for the evaluation of degenerative joint disease, by examining alterations in tissue birefringence in articular cartilage specimens. Tissue birefringence is influenced by both the material composition of the tissue and its orgainization and orientation in relation to the optical axis. Non-linear optical microscopy is being used to describe the organization and orientation of collagen fibers in articular cartilage specimens imaged by PS-OCT in order to better interpret the phase retardation images obtained from articular cartilage specimens.
该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者(PI)可能从另一个NIH来源获得主要资金,因此可以在其他CRISP条目中表示。所列机构为中心,不一定是研究者所在机构。通过检查关节软骨标本中组织双折射的变化,对偏振敏感光学相干断层扫描(PS-OCT)作为评价退行性关节疾病的潜在诊断工具进行了评价。组织双折射受组织的材料组成及其相对于光轴的组织和取向的影响。非线性光学显微镜被用来描述组织和取向的胶原纤维在关节软骨标本成像PS-OCT,以更好地解释从关节软骨标本获得的相位延迟图像。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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TATIANA B KRASIEVA其他文献
TATIANA B KRASIEVA的其他文献
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{{ truncateString('TATIANA B KRASIEVA', 18)}}的其他基金
BIO-POD: PALLET MICRO-ARRAY FOR RARE CELL ANALYSIS
BIO-POD:用于稀有细胞分析的托盘微阵列
- 批准号:
8362628 - 财政年份:2011
- 资助金额:
$ 2.65万 - 项目类别:
MPM STUDY OF ANIMAL SYNOVIUM TO OBTAIN INSIGHT INTO AFFECTS OF ARTHRITIS
对动物滑膜进行 MPM 研究以深入了解关节炎的影响
- 批准号:
8362631 - 财政年份:2011
- 资助金额:
$ 2.65万 - 项目类别:
IMAGING VULNERABLE PLAQUE IN ATHEROSCLEROTIC MICE
动脉粥样硬化小鼠中易损斑块的成像
- 批准号:
8362630 - 财政年份:2011
- 资助金额:
$ 2.65万 - 项目类别:
NONINVASIVE IMAGING OF NEURAL STEM AND PRECURSOR CELL FUNCTIONS
神经干和前体细胞功能的无创成像
- 批准号:
8362632 - 财政年份:2011
- 资助金额:
$ 2.65万 - 项目类别:
MULTI-PHOTON IMAGING OF ACTIN FILAMENT FORMATION AND MITOCHONDRIAL ENERGETICS
肌动蛋白丝形成和线粒体能量的多光子成像
- 批准号:
8362658 - 财政年份:2011
- 资助金额:
$ 2.65万 - 项目类别:
COMBINED TWO PHOTON OPTICAL COHERENCE MICROSCOPY FOR INTRAVITAL FUNCT IMAGING
用于活体功能成像的组合两个光子光学相干显微镜
- 批准号:
8362594 - 财政年份:2011
- 资助金额:
$ 2.65万 - 项目类别:
OPTICAL AND MOLECULAR APPROACHES TO THE STUDY OF CHEMICAL AGENTS
研究化学试剂的光学和分子方法
- 批准号:
8362624 - 财政年份:2011
- 资助金额:
$ 2.65万 - 项目类别:
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