课题基金 / 基金详情

Phase I Study of Topical Romidepsin in Early Stage Cutaneous T-cell Lymphoma

Phase I Study of Topical Romidepsin in Early Stage Cutaneous T-cell Lymphoma
局部用罗米地辛治疗早期皮肤 T 细胞淋巴瘤的 I 期研究
批准号：
7965835
负责人：
Heidi Kong
金额：
$10.1万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7965835
关键词：
Adverse effectsBiological MarkersBiopsyBloodCD4 Positive T LymphocytesCarmustineChronicClinical TrialsClinical trial protocol documentCutaneousCutaneous LymphomaDepsipeptidesDiseaseDoseDrug KineticsEarly treatmentElectron Beam TherapyErythemaEvaluationFicusinHistologyHistone Deacetylase InhibitorIndividualIonizing radiationMechlorethamineMycosis FungoidesNon-Hodgkin&aposs LymphomaPatientsPharmaceutical PreparationsPhase I Clinical TrialsPhotographyPhototherapyPhysical ExaminationPruritusPsoralensQuality of lifeRadiationRadiation therapyRecruitment ActivityRecurrenceRefractoryResearchRiskSafetySkinSkin CancerStagingT-Cell LymphomaTimeUltraviolet RaysVorinostatcosteffective therapyresearch studyskin disorder

项目摘要

项目成果

Heidi Kong的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
We have been actively recruiting for this clinical trial protocol of the safety and efficacy of topical romidepsin (depsipeptide) in early stage mycosis fungoides (a rare type of skin lymphoma). In fiscal year 2009, we completed two dose levels. Each dose level evaluation includes repeated assessments of skin disease through physical examination, medication tolerability, pruritus, quality of life, erythema with the use of colorimeter, photography using a standardized studio set-up, research blood for side effect evaluation and pharmacokinetics, and skin biopsies for routine histology and special research studies.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Effects of systemic and topical perturbations on human microbes
Botulinum Toxin for Painful Cutaneous Leiomyomas
Effects of systemic and topical perturbations on human microbes
Botulinum Toxin for Painful Cutaneous Leiomyomas
海外基金