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中文摘要
翻译
生物统计共享资源(BSR)的使命是作为癌症中心的协调中心 成员在设计,管理和分析他们的研究获得援助。的服务 由BSR提供的包括: 1.在临床试验、观察性研究的设计中进行生物统计学合作和咨询, 实验室研究一个适当的统计设计是必要的,如果研究是成功的, 实现其科学目标。 2.数据分析方面的统计专业知识。所采用的具体方法取决于随机化或 特定项目的抽样设计和规模(二进制,有序分类,或连续) 被调查的结果变量。统计数据分析使用 封装和专用计算机程序。 3.临床试验的科学审查、质量控制、数据和安全性监测。 4.教育;通过正式和非正式的研讨会、课程和讲座;以及 满足癌症中心研究的科学目标所需的统计方法。在 一般来说,BSR试图强调与 在整个研究过程中,生物统计学家,而不是一次性的咨询,没有适当的 上下文
英文摘要
The mission of the Biostatistics Shared Resource (BSR) is to serve as a focal point for cancer center members to obtain assistance in the design, management, and analysis of their studies. The services provided by the BSR include: 1. Biostatistical collaboration and consultation in the design of clinical trials, observational studies, and laboratory studies. An appropriate statistical design is necessary if the research is to be successful in fulfilling its scientific objectives. 2. Statistical expertise in data analysis. The specific methods employed depend on the randomization or sampling design of the particular project and on the scale (binary, ordered categorical, or continuous) of the outcome variable being investigated. Statistical data analyses are performed using both packaged and special purpose computer programs. 3. Scientific review, quality control, and data and safety monitoring for clinical trials. 4. Education; through formal and informal seminars, courses and lectures; and the development of statistical methodology necessary for meeting the scientific objectives of cancer center studies. In general, the BSR attempts to emphasize the importance of ongoing and continuing collaboration with biostatisticians during the entire research effort, rather than one-time consultation without appropriate context.
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Adaptive signaling exposes a therapeutic vulnerability in NRAS melanomas
  • 批准号:
    8621637
  • 项目类别:
  • 资助金额:
    $20.62万
  • 财政年份:
    2014
  • 负责人:
    MICHAEL J. WEBER
  • 依托单位:
Senior Leadership
  • 批准号:
    8724657
  • 项目类别:
  • 资助金额:
    $2.08万
  • 财政年份:
    2013
  • 负责人:
    MICHAEL J. WEBER
  • 依托单位:
Senior Leadership
  • 批准号:
    8719585
  • 项目类别:
  • 资助金额:
    $2.5万
  • 财政年份:
    2013
  • 负责人:
    MICHAEL J. WEBER
  • 依托单位:
Senior Leadership
  • 批准号:
    8231151
  • 项目类别:
  • 资助金额:
    $38.41万
  • 财政年份:
    2012
  • 负责人:
    MICHAEL J. WEBER
  • 依托单位:
海外基金