Emerging Topics in Immune System Plasticity: Cellular Networks, Metabolic Control
免疫系统可塑性的新兴主题:细胞网络、代谢控制
基本信息
- 批准号:8400276
- 负责人:
- 金额:$ 1.1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-01-01 至 2013-12-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAgingAnimal ModelAreaAutoimmunityAwarenessBiological ProcessBiologyCell CommunicationCell divisionCell physiologyCellsCellular biologyCharacteristicsCollaborationsCommunitiesDefense MechanismsDevelopmentDevelopmental ProcessDisciplineDissectionEmbryoEquilibriumFeedbackFosteringGenerationsGenetic TranscriptionGenomeHomeostasisHumanHypersensitivityImmuneImmune responseImmune systemImmunityImmunologicsImmunologistImmunologyInfectionKnowledgeLeadLymphocyteLymphoidMalignant NeoplasmsMentorsMetabolicMetabolic ControlMetabolismMolecular BiologyNatural regenerationNatureNeoplastic ProcessesNew MexicoOrganOutcomeParticipantPathway AnalysisPostdoctoral FellowReactionResearchResearch PersonnelSignal TransductionStagingStem cellsSurfaceSystemSystems BiologyTissuesTrainingVertebratesViralassaultcell behaviorcell growthcell typecombatdoctoral studentfluidityimprovedmeetingsmicrobialposterspre-doctoralpreventpublic health relevanceregenerativeresponseself-renewalsymposiumsystems researchtool
项目摘要
Description (as provided by the applicant): Support is requested for a Keystone Symposia meeting entitled Emerging Topics in Immune System Plasticity: Cellular Networks, Metabolic Control, and Regeneration, organized by Steven L. Reiner, Erika L. Pearce and Yasmine Belkaid. The meeting will be held in Santa Fe, New Mexico from January 15 - 20, 2013. The immune system is a multi-cellular network that adapts to external threats. Immune cells cooperate with other defenses, such as barriers, to prevent breach and to reject invaders by selecting the right responses while inflicting minimal damage to the host. A key feature of the immune system is its fluidity and ability to traverse temporal and spatial boundaries. Furthermore, immune system dynamics involve cellular expansion, provisional cellular niches, altered transcription, and balancing differentiation with regeneration. This meeting will bring together diverse researchers to better understand how immune reactions are orchestrated to contend with the extrinsic information and metabolic demands of cellular differentiation, function,
and homeostasis. The aims of the meeting are to 1) unveil the nature of cell-to-cell communication that occurs during different stages of the immune response, 2) reveal the latest understanding of extrinsic and intrinsic signaling networks that dictate lymphocyte and other immune cell fates, 3) increase awareness of metabolic control of immune cell fate and function, and 4) provide a format for the training and mentoring of new investigators and pre- and post- doctoral students. We anticipate that this meeting will alter the field's view of immune mobilization and execution, and will help to break barriers between immunology and other disciplines.
描述(由申请人提供):请求支持由Steven L.组织的题为免疫系统可塑性的新兴主题:细胞网络、代谢控制和再生的Keystone研讨会会议。作者:Reiner,Erika L.皮尔斯和雅斯敏·贝尔凯德。会议将于2013年1月15日至20日在新墨西哥州圣达菲举行。免疫系统是一个适应外部威胁的多细胞网络。免疫细胞与其他防御系统(如屏障)合作,通过选择正确的反应来防止突破并拒绝入侵者,同时对宿主造成最小的伤害。免疫系统的一个关键特征是它的流动性和穿越时间和空间边界的能力。此外,免疫系统动力学涉及细胞扩增、临时细胞小生境、改变的转录以及平衡分化与再生。这次会议将汇集不同的研究人员,以更好地了解免疫反应是如何协调,以应对细胞分化,功能,
和体内平衡。会议的目的是1)揭示免疫反应不同阶段发生的细胞间通讯的本质,2)揭示决定淋巴细胞和其他免疫细胞命运的外在和内在信号网络的最新理解,3)提高对免疫细胞命运和功能的代谢控制的认识,(4)为新的研究人员和博士前和博士后学生提供培训和指导的形式。我们预计,这次会议将改变免疫动员和执行领域的观点,并将有助于打破免疫学和其他学科之间的障碍。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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James Wavell Aiken其他文献
James Wavell Aiken的其他文献
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- 资助金额:
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