NEUROENDOCRINE FACTORS IN ADOLESCENT OBESITY

青少年肥胖的神经内分泌因素

• 批准号: 7731256
• 负责人: ANNE KLIBANSKI
• 金额: $ 0.05万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731256
• 关键词: Adolescent; Age; Body Composition; Computer Retrieval of Information on Scientific Projects Database; Desire for food; Development; Employee Strikes; Epidemic; Female Adolescents; Funding; Grant; Hormones; Institution; Insulin; Insulin Resistance; Neurosecretory Systems; Obesity; Overweight; Pattern; Research; Research Personnel; Resources; Somatotropin; Source; Stomach; United States National Institutes of Health; Weight; age group; ghrelin; increased appetite

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Obesity is an epidemic that is striking people at younger ages than ever before. Obesity is associated with changes in the secretory patterns of several hormones including ghrelin, growth hormone (GH), and insulin, which have not been examined in the adolescent age group. Ghrelin, a hormone produced mainly in the stomach, increases appetite and causes GH secretion. This study will compare the change in secretion of ghrelin and GH in overweight and normal weight adolescent girls. Understanding obesity-related changes in ghrelin and GH and their relationship to body composition, insulin resistance, and appetite will help in the development of strategies to reduce complications of obesity.

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