HORMONE DYNAMICS AND BONE MINERAL DENSITY IN ANOREXIA NERVOSA VS HA (SEE 0630)

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 神经性厌食症（AN）和下丘脑性闭经（HA）是一种低雌激素状态，伴有骨质丢失。AN中发生的骨丢失比HA中更严重，暗示营养缺乏的额外影响。激素异常，包括高皮质醇血症，见于这两种疾病。在这项研究中，我们将比较骨密度，激素的变化，并与女性相比，HA和健康对照组的女性与AN的身体成分。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Anorexia nervosa (AN) and hypothalamic amenorrhea (HA) are hypoestrogenic states accompanied by bone loss. The bone loss that occurs in AN is more severe than in HA, implicating an additional effect of nutritional deficiencies. Hormonal abnormalities, including hypercortisolemia, are seen in both disorders. In this study we will compare bone density, hormonal changes, and body composition in women with AN compared to women with HA and healthy controls.