HORMONE DYNAMICS AND BONE MINERAL DENSITY IN ANOREXIA NERVOSA VS HA (SEE 0630)

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 神经性厌食症(AN)和下丘脑闭经(HA)是伴有骨质丢失的低雌激素状态。发生在AN中的骨丢失比在HA中发生的更严重，这意味着营养缺乏的额外影响。激素异常，包括高皮质醇血症，在这两种疾病中都可以看到。在这项研究中，我们将比较患有骨质疏松症的女性与患有HA的女性和健康对照组的骨密度、激素变化和身体成分。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Anorexia nervosa (AN) and hypothalamic amenorrhea (HA) are hypoestrogenic states accompanied by bone loss. The bone loss that occurs in AN is more severe than in HA, implicating an additional effect of nutritional deficiencies. Hormonal abnormalities, including hypercortisolemia, are seen in both disorders. In this study we will compare bone density, hormonal changes, and body composition in women with AN compared to women with HA and healthy controls.