B WELL MOM FATTY ACID PROFILE

呼吸健康、环境、生活方式和肺功能研究(B-Well妈妈研究)的目的是检查哮喘控制在妊娠结局中的作用。这项研究从孕期免疫学和遗传、环境和社会健康决定因素等风险因素的角度考察了哮喘控制不良的情况。 有哮喘和无哮喘的妇女在怀孕的前三个月(妊娠15周)和产后4个月被纳入。评估发生在怀孕的每三个月(15周、20-22周、30-32周)、分娩时和产后4个月。 B-Well妈妈研究在每次访问(15周、20-22周、30-32周)和产后4个月收集了大约400名受试者的尿液、微生物拭子和血液样本(PAX基因RNA、血清、血浆和黄褐色外套)。孕期采集一次鼻拭子，分娩时采集胎盘组织标本和脐带血RNA。

The purpose of the Breathe – Wellbeing, Environment, Lifestyle and Lung Function Study (B-WELL Mom Study) is to examine the role of asthma control in pregnancy outcomes. This study examines poor asthma control in the context of the immunology of pregnancy and risk factors such as genetics, the environment, and social determinants of health. Women with and without asthma were recruited during the first trimester of pregnancy (< 15 weeks gestation) and followed through 4 months post-partum. Assessments occurred during each trimester of pregnancy (<15 weeks, 20-22 weeks, 30-32 weeks), at delivery, and 4 months post-partum. The B-WELL Mom study collected urine, microbiome swabs, and blood samples (PAXGene RNA, serum, plasma, and buffy coat) from approximately 400 subjects at each visit (<15 weeks, 20-22 weeks, 30-32 weeks) and 4 months post-partum. Nasal swabs were collected once during pregnancy, and placental tissue specimens and cord blood RNA were collected at delivery.