The in vivo and in vitro biology of the novel intracellular ion channel CLIC1 (NCC27)
The in vivo and in vitro biology of the novel intracellular ion channel CLIC1 (NCC27)
批准号:
nhmrc : 300499
负责人:
Prof Jamie Vandenberg
金额:
$28.86万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2004
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2004-01-01 至 2006-12-31
中文摘要
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英文摘要
Ion channels are complex proteins that regulate the transports of salts, and essential cell function. We have recently cloned a new ion channel, CLIC1, unique in its location on the nuclear membrane as well as other sites. The function of this channel is uncertain, although we have suggested its association with cell growth and inflammation. We propose to investigate the function of CLIC1, dominantly based on gene knockout animals, in which the CLIC1 gene has been deleted.
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国内基金
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