CARDIOVASCULAR AND METABOLIC PERFORMANCE IN HIGHLY TRAINED OLDER MEN

发生的心血管和代谢储备的功能性下降 随着年龄的增长，可能不仅仅是由于生物衰老，而是可能 部分源于伴随着越来越多的久坐的生活方式 衰老。确定体力活动在保存功能方面的作用 能力，我们测量了身体成分，最大有氧能力 最大摄氧量(VO2max)、安静时的心脏容量、最大限度的自行车运动和 下体负压、血脂和糖耐量异常19例 训练有素的男子(T)，年龄60-76岁。与11种健康瘦肉的比较 久坐对照(C)如下所示。 T C P 年龄65+/-1 65+/-2纳氏 体脂百分比14+/-1 15+/-1纳秒 最大摄氧量(毫升/公斤/分钟)51+/-1 30+/-2小于0.01 低密度脂蛋白(毫克/分升)117+/-5 129+/-10毫微秒 高密度脂蛋白胆固醇(mg/dl)59+/-3 49+/-3低于0.05 甘油三酯76+/-4 112+/-10 nS 空腹血糖(mg/dl)93+/-2 98+/-2低于0.05 2小时餐后血糖(mg/dl)104+/-6 124+/-3低于0.05 均值+/-扫描电子显微镜 因此，在老年男性中，高水平的体力活动似乎会减弱 与年龄相关的心血管和代谢功能下降。

The functional decline in cardiovascular and metabolic reserve which occurs with advancing age may not be solely attributed to biological aging but may derive in part from the increasingly sedentary life style that accompanies aging. To determine the role of physical activity in preserving functional capacity, we have measured body composition, maximal aerobic capacity (VO2max), cardiac volumes at rest, during maximal bicycle exercise and lower body negative pressure, blood lipids and glucose tolerance in 19 highly trained men (T) aged 60-76 years. A comparison with 11 healthy lean sedentary controls (C) is shown below. T C P Age 65 +/- 1 65 +/- 2 NS % body fat 14 +/- 1 15 +/- 1 NS VO2max (ml/kg/min) 51 +/- 1 30 +/- 2 less than .01 LDL cholesterol (mg/dl) 117 +/- 5 129 +/- 10 NS HDL cholesterol (mg/dl) 59 +/- 3 49 +/- 3 less than .05 Triglycerides 76 +/- 4 112 +/- 10 NS Fasting glucose (mg/dl) 93 +/- 2 98 +/- 2 less than .05 2 hr postprandial glucose (mg/dl) 104 +/- 6 124 +/- 3 less than .05 Mean +/- SEM Thus in older men, high levels of physical activity appear to attenuate age-related declines in cardiovascular and metabolic function.