STUDY OF NORMAL HUMAN VARIABILITY AND CROSS CULTURAL AGING

该项目是一项持续的合作努力，世卫组织和 其他国家和国际实验室协调收集， 普通遗传标记在研究中的评价和解释 遗传因素和外来因素的跨文化模式 与正常老龄化和起病较晚的疾病有关，包括 阿尔茨海默病、乳腺癌、肌萎缩侧索硬化症 帕金森痴呆症。具体而言，这项研究的目标是：a) 研究中国人遗传因素和非遗传因素的跨文化模式 努力更好地理解标准老化的过程。B)研究 晚发性家系中这些标记的遗传分离 阿尔茨海默氏症、乳腺癌、肌萎缩侧索硬化症等疾病 努力建立遗传联系并最终确定 导致这些疾病的因素。C)研究……的分布 BLSA的皮纹学、侧向显性和其他遗传变量 受试者和其他对照样本，以及晚期 发病的疾病。

This project represents an ongoing collaborative effort, involving WHO and other national and international laboratories to coordinate the collection, evaluation and interpretation of normal genetic markers in order to study the cross-cultural patterns of genetic and extraneous factors as they relate to normative aging and to diseases with late onset, including Alzheimer's disease, breast cancer, Amyotrophic Lateral Sclerosis, and Parkinsonism Dementia. Specifically, the objectives of this study are: A) To study the cross cultural patterns of genetic and non-genetic factors in an effort to better understand the process of normative aging. B) To study the genetic segregation of these markers in families with late onset diseases, such as Alzheimer's disease, breast cancer, ALS and others, in an effort to establish genetic linkages and eventual identification of the factors responsible for these diseases. C) To study the distribution of dermatoglyphics, lateral dominance and other genetic variables in BLSA participants and other control samples, as well as in patients with late onset diseases.