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EXTRACELLULAR MATRIX SYNTHESIS BY HUMAN TUMORS IN VITRO

EXTRACELLULAR MATRIX SYNTHESIS BY HUMAN TUMORS IN VITRO
人类肿瘤的体外细胞外基质合成
批准号:
3939190
负责人:
T J TRICHE
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
人类合成的基质蛋白的种类和数量 体外培养的肿瘤细胞似乎与培养的正常细胞相似 在某种程度上,细胞对应物。我们已经扩大了这些 观察各种人类肿瘤以确定是否 这些模式可能允许更精确地对 肿瘤的起源。此外,我们正在描述一种新的矩阵 由其中一些肿瘤合成的蛋白质。身份, 细胞外的功能和分子组织 此组件的矩阵目前未知。
英文摘要
The type and amount of matrix proteins synthesized by human tumor cells in vitro appears to parallel that of cultured normal cell counterparts to some extent. We have broadened these observations to a variety of human tumors to determine whether these patterns might allow more precise categorization of the tumor's origins. In addition, we are characterizing a new matrix protein synthesized by some of these tumors. The identity, function, and molecular organization within the extracellular matrix of this component is currently unknown.
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