Decrypting the Excitation Contraction coupling machinery in skeletal muscle
Decrypting the Excitation Contraction coupling machinery in skeletal muscle
批准号:
nhmrc : GNT1126201
负责人:
A/Pr Aaron Oakley
金额:
$91.49万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --
中文摘要
骨骼肌的功能依赖于对钙水平的精细控制。当肌肉中关键蛋白质的通讯受到影响时,钙水平就会失控,导致严重的残疾。控制关键肌肉蛋白之间信号传递的分子通路目前尚不清楚,揭示这一主题将有助于发现治疗疾病和衰老中肌肉相关残疾的方法。
英文摘要
Skeletal muscle function is dependent upon the fine control of calcium levels. When communication of key proteins in muscle are compromised, calcium levels are uncontrolled leading to severe disabilities. The molecular pathways that control signalling between key muscle proteins is currently unknown and shedding light on this topic will aid in the discovery of therapies for muscle-associated disabilities in disease and with aging.
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会议论文
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依托单位:
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依托单位:
Decrypting the Excitation Contraction coupling machinery in skeletal muscle
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依托单位:
海外基金