STUDIES OF VISUAL PROCESSING & SMOOTH EYE MOVEMENTS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。我们的研究旨在定义与平滑追求眼球运动和凝视相关的视觉处理的神经基质。我们正在努力确定早期视觉体验与眼球运动系统、眼睛对准和凝视之间的关系。视觉和动眼力系统在出生时并不成熟。如果早期的视觉体验受到损伤或先天性缺陷的影响，眼动障碍可能会随之而来，从而影响清晰的视力。我们最近首次证明了MST皮层的神经元具有适当的响应特性，在视差收敛中发挥作用。我们现在正在尝试针对眼睛对准、立体视和收敛发育的关键时期进行研究。我们还进行了研究，证明了主动和被动视觉运动的视觉延迟的差异。这些发现表明，在对视觉场景进行主动扫描的过程中，视觉延迟时间减少，这可能有助于扫视过程中的视觉。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Our studies are directed at defining the neural substrate for visual processing related to smooth pursuit eye movements and gaze-holding. We are working to define the relationship between early visual experience and development of eye movement systems, eye alignment and gaze holding. The visual and oculomotor systems are not mature at birth. If early visual experience is compromised by injury or congenital defect, eye movement disorders can follow that can compromise clear vision. We have recently demonstrated for the first time that neurons in MST cortex have appropriate response properties to play a role in disparity vergence. We are now attempting studies that target the critical period in development of eye alignment, stereopsis and vergence. We have also conducted studies that demonstrate differences in visual latency for active and passive visual motion. These findings suggest that during active scanning of a visual scene that visual latencies are reduced, perhaps facilitating vision during saccades.