Core 2: Brain mapping (267-289)

这个核心的主要目标是提供脑图专业知识，这两个方面都是关于磁学 共振成像和电生理技术，用于项目1、2、3和5。该核心将 能够在神经生物学和心理分析水平上进行检查，明确解决 在我们对执行职能的理解中，中心目标是将分析层级联系起来。该核心将提供： A)核磁共振和企业资源规划数据的质量控制、储存、分析和存档； B)记录数据结构和处理程序 C)将新的分析工具纳入数据分析路径 D)支持工作人员进行脑图实验 E)对这些研究方法进行培训，并为培训目的编写材料 F)为数据共享和其他相关职能编制数据 在神经成像方面，这一核心还将提供： A)安装系统升级和硬件改进 B)开发新的采集和前处理方法，特别是处理 磁化率伪影和低信噪比。 C)将新的统计方法应用于数据分析 D)如果观察到参与者有任何结构异常，应具备临床专长 关于电生理技术，该核心还将提供： A)高密度阵列记录系统的数据收集标准化 B)扩展整合功能磁共振成像和企业资源规划实验数据的方法和途径 是并行设计的。更具体地说，它将研究fMRI数据可用于 企业资源规划数据的种子偶极子源，以及这些源可如何解开的方法。 了解神经生物标志物和心理功能之间的关系有很大的意义。 对心理健康的影响。它为新的诊断和诊断程序提供了一条潜在的途径 与精神障碍相关的执行功能障碍的治疗效果评估。

The main goal of this core is to provide the brain mapping expertise, both with regards to magnetic resonance imaging and electrophysiological techniques, for use in Projects 1,2,3, and 5. This core will enable examination at both the neurobiological and psychological levels of analysis, explicitly addressing a center goal of linking levels of analysis in our understanding of executive function. The core will provide for: a)the quality control, storage, analysis and archiving of MRI and ERP data; b) documentation of data structures and processing procedures c) the incorporating of new analytic tools into the data analysis path d) support staff for running brain mapping experiments e) training in these research methods as well as the creation of materials for training purposes f) preparation of data for data sharing, and other associated functions With regards to neuroimaging, this core will also provide: a) installation of system upgrades and improvements to hardware b) the development of new acquisition and pre-processing methods, especially those that deal with susceptibility artifact and low signal-to-noise ratio. c) the application of new statistical methods to data analysis d) clinical expertise should any structural abnormalities be observed in participants With regards to electrophysiological techniques, this core will also provide: a) standardization of data collection across high-density array recording system b) expand methods and approaches for the integration of data from fMRI and ERP experiments that have been designed in parallel. More specifically it will examine various ways in which fMRI data can be used to seed dipole sources for ERP data, and the ways in which these sources can be disentangled. Understanding the relationship between neurobiological markers and psychological functioning has large implications for mental health. It provides a potential avenue for new procedures for diagnosis and assessment for the efficacy of treatment for executive dysfunction associated with psychiatric disorders.