Neurologic Clinical Epidemiology Training Program

临床流行病学和生物统计中心(CCEB)和美国疾病控制与预防中心 宾夕法尼亚大学(宾夕法尼亚大学)医学院与 费城儿童医院神经科儿科建议开发一种创新的 博士后神经学临床流行病学培训计划。宾夕法尼亚州立大学和SOM推动一位学者 鼓励基础和临床研究并将其视为有吸引力的职业道路的环境 实习生。该机构还吸引了全国其他机构的学员，从而促进了 想法和指导风格。 这一计划是专门为培训已经接受过神经学培训的临床医生而设计的， 独立的学术研究人员能够使用流行病学中可用的一系列方法来 解决临床研究问题，包括病因、预后、预防和早期发现、治疗、 临床经济学、技术评估、医疗决策和患者护理质量 神经系统疾病。具体地说，受训者将把临床流行病学的方法应用于广泛的 神经病学中的子专科，包括神经眼科、多发性硬化症、神经病学- 肿瘤学、癫痫、认知神经学、中风和运动障碍。 为期两到三年的培训计划包括临床流行病学、研究等必修课程 方法论、生物统计学和神经学临床流行病学；期刊俱乐部和临床研究 专注于神经学研究问题的会议；广泛的独立阅读；出席和 参加CCEB、神经内科和神经内科的研究研讨会 (儿科学)；以及完成一项独立研究项目。具体地说，该计划旨在： (1)提供适合临床研究的研究技术的深入知识；。(2)提供 与导师在临床流行病学和神经学研究方面的研究经验；以及(3)将 CCEB、神经内科和神经科(儿科)的教职员工和研究员。 学员攻读临床流行病学理学硕士学位课程，该学位课程是 由CCEB管理。 拟议计划的优点是：1)成功的研究培训计划在 CCEB；2)向学员提供的综合课程和研究计划；3) CCEB、神经内科和科室之间的合作关系 神经学(儿科学)；4)和一批经验丰富的项目主任和教员，他们拥有 成功的培训记录。此外，各学院拥有广泛而丰富的专业知识 CCEB、神经内科和神经内科(儿科)；许多现有的大型 可用于研究项目和培训的可用数据库；广泛的专业分析 可用于临床研究的能力(即临床试验、病例对照、队列研究)； 致力于合作研究和培训，为本培训计划提供了理想的环境。

The Center for Clinical Epidemiology and Biostatistics (CCEB) and the Department of Neurology of the University of Pennsylvania (Penn) School of Medicine (SOM), in collaboration with the Department of Pediatrics, Division of Neurology, of Children's Hospital of Philadelphia propose to develop an innovative post-doctoral neurologic clinical epidemiology training program. Penn and the SOM promote an academic environment in which basic and clinical research are encouraged and viewed as attractive career paths for trainees. The institution also attracts trainees from other institutions nationwide, thus promoting exchange of ideas and mentoring styles. This program is specifically designed to train clinicians already trained in neurology to be rigorous, independent academic investigators able to use the range of approaches available in epidemiology to address clinical research issues regarding the etiology, prognosis, prevention and early detection, treatment, clinical economics, technology assessment, medical decision making, and quality of patient care of neurologic diseases. Specifically, trainees will apply the methods of clinical epidemiology to a broad spectrum of sub-specialties within Neurology, including neuro-ophthalmology, multiple sclerosis, neuro- oncology, epilepsy, cognitive neurology, stroke, and movement disorders. The two- to three-year training program consists of required courses in clinical epidemiology, research methodology, biostatistics, and neurologic clinical epidemiology; journal clubs and clinical research conferences focusing on research issues in neurology; extensive independent readings; attendance at and participation in research seminars at the CCEB, Department of Neurology, and Division of Neurology (Pediatrics); and the completion of an independent research project. Specifically, the program is designed to: (1) provide in-depth knowledge of the research techniques appropriate to clinical research; (2) provide research experience with mentors in clinical epidemiology and neurology research; and (3) bring together faculty and fellows in the CCEB, the Department of Neurology, and the Division of Neurology (Pediatrics). Trainees matriculate in the Master of Science in Clinical Epidemiology (MSCE) degree program, which is managed by the CCEB. Strengths of the proposed program are: 1) the long history of successful research training programs in the CCEB; 2) the comprehensive course offerings and research programs that are available to trainees; 3) the collaborative links that exist among the CCEB, the Department of Neurology, and the Division of Neurology (Pediatrics); 4) and an extensive set of experienced program directors and faculty preceptors with successful training records. In addition, the availability of the broad range of rich expertise of the faculties in the CCEB, Department of Neurology, and Division of Neurology (Pediatrics); numerous existing large databases available that can be used for research projects and training; a broad array of specialized analytic capabilities available for clinical studies (i.e., clinical trials, case-control, cohort research); and the faculties' commitment to collaborative research and training, provide an ideal environment for this training program.