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Human Exposure To Halogenated Aromatic Compounds

Human Exposure To Halogenated Aromatic Compounds
人类接触卤化芳香族化合物
批准号：
8336536
负责人：
WALTER ROGAN
金额：
$4.31万
依托单位：
NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8336536
关键词：
Aromatic CompoundsCensusesCessation of lifeChemicalsDataEvaluationExcess MortalityExposure toHealthHumanLiver diseasesLupusMalignant NeoplasmsNon-MalignantOilsPersonsPoisoningPolychlorinated BiphenylsPublic HealthRegistriesReportingTaiwanTimeUpdatecohortcookingexposed human populationhealth organizationmalignant stomach neoplasmmortality

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中文摘要
翻译
利用台湾死亡登记处和中毒受害者普查的数据，我们比较了PCB暴露发生后28年的死亡率。 这是第一次出现癌症死亡率过高的情况，特别是胃癌。 这增加了多个公共卫生组织关于这些化学物质对人类致癌的评估的一致性。 系统性红斑狼疮的死亡人数也出乎意料地多，这在暴露于类似化学物质的其他队列中还没有发现。
英文摘要
Using data from the Taiwanese death registry and the census of victims of the poisoning, we compared mortality at 28 years after the PCB exposure occurred. For the first time, there was excess mortality from cancer, specifically stomach cancer. This adds consistency to the evaluations made by several public health organizations that these chemicals are carcinogenic for humans. There was also an unexpected excess of deaths from systemic lupus, which has not been seen in other cohorts exposed to similar chemicals.
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HUMAN EXPOSURE TO HALOGENATED AROMATIC COMPOUNDS
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