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Toxicity Of Lead In Children--Clinical Trial

Toxicity Of Lead In Children--Clinical Trial
铅对儿童的毒性--临床试验
批准号:
8734064
负责人:
WALTER ROGAN
金额:
$22.48万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
我们进行了琥珀酸类药物治疗中度铅中毒儿童的临床试验。我们没有发现琥珀酸治疗对认知或行为的影响,这是先前报道的。最近,我们已经与疾控中心安排对该项目中采集的血液样本进行甲基汞、无机汞和镉的分析,这允许在不招募任何新的受试者或收集任何样本的情况下,对琥珀酸络合这些化合物进行随机试验。蔗糖分子似乎不是汞或镉的有效螯合剂。
英文摘要
We did a clinical trial of succimer to treat moderately lead poisoned children. We found no effect of succimer treatment on cognition or behavior, reported previously. Recently, we have arranged with CDC to analyze blood samples collected in this project for methyl mercury, inorganic mercury, and cadmium, which allowed a randomized trial of succimer for chelation of these compounds without enrolling any new subjects or collecting any specimens. Succimer does not appear to be an efficacious chelating agent for mercury or cadmium.
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HUMAN EXPOSURE TO HALOGENATED AROMATIC COMPOUNDS
Human Exposure To Halogenated Aromatic Compounds
Human Exposure To Halogenated Aromatic Compounds
Toxicity Of Lead In Children--Clinical Trial
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