Comprehensive Musculoskeletal Training Program

摘要 在综合肌肉骨骼训练计划的前三年，我们已经完全填满了所有 授予的培训名额。我们已经培养了6名博士前学生(其中1名是医学博士/博士生)， 5名博士后研究员和6名暑期医学生实习生(包括接受3名暑期医学生 2018年夏季会议的实习生)。目前，所有的职位都已填满。我们在这份续期申请中建议 将每组实习生职位从三个增加到四个：博士后、博士后 研究员和暑期医学生实习生，额外的博士后名额预留一年 骨科住院医师的研究轮换。自上次提交以来，有几项新的进展 已经发生了加强培训计划，使其更加多学科的受训者，并提供 基础、翻译和临床培训和研究之间有更多的交流机会。这些措施包括 建立印第安纳州肌肉骨骼健康中心(ICMH)(有一名全职主任)，创建 通过NIH P30拨款授予ICMH临床研究核心，并提议建立一个新的 肌肉骨骼学博士课程。综合肌肉骨骼训练计划的目标是 (1)扩大和整合现有的肌肉骨骼研究和教学计划，包括基础、临床和 工程科学；(2)培养从事研究的博士后和博士后青年科学家 基础科学家、生物工程师、临床和翻译研究人员的职业生涯 解决肌肉骨骼疾病；以及(3)培训博士后和博士后学生/研究员 国家博士后协会列出的六项核心能力。主要活动将包括 开发特定学科的知识库，发展研究技能，并加强 沟通能力、专业性、领导力和管理能力，以及对责任人的培训 研究的进行。该计划包括30名培训教师，分为四个主要轴：内分泌学， 骨细胞生物学、肌肉骨骼癌、机械生物学和力学。其中每一个都有三个 不同的重点小组，所有受训人员都必须有来自其中一个以上培训舱的导师。 培训计划描述包括受训人员的活动清单、对导师的要求、教学内容 和职业发展计划，以及对实习生、导师和整体 培训计划。

Abstract In the first three years of the Comprehensive Musculoskeletal Training Program, we have completely filled all the training slots awarded. We have trained six predoctoral students (one a combined degree MD/PhD student), five postdoctoral fellows, and six summer medical student interns (including acceptance of 3 summer medical interns for the 2018 summer session). Currently, all slots are filled. We propose in this renewal application to expand the number of trainee positons from three to four for each group: predoctoral students, postdoctoral fellows, and summer medical student interns, with the additional postdoctoral slot reserved for a one-year research rotation for a resident in orthopaedic surgery. Since the last submission, several new developments have occurred that strengthen the training program, making it more multi-disciplinary for trainees, and providing greater opportunities for cross talk between basic, translational, and clinical training and research. These include the establishment of the Indiana Center for Musculoskeletal Health (ICMH) (with a full-time Director), the creation of the ICMH Clinical Research Core through a NIH P30 grant award, and a proposal to establish a new Musculoskeletal PhD program. The goals of the Comprehensive Musculoskeletal Training Program are to (1) expand and integrate current musculoskeletal research and teaching programs in the basic, clinical, and engineering sciences; (2) train young scientists at both the predoctoral and postdoctoral levels for research careers as basic scientists, bioengineers, clinical and translational investigators pursuing the causes of, and solutions to, musculoskeletal disease; and (3) train both predoctoral and postdoctoral students/fellows, according to the six Core Competencies outlined by the National Postdoctoral Association. Key activities will include the development of a discipline-specific knowledge base, research skill development, and enhancement of communication skills, professionalism, leadership and management skills, and training in the Responsible Conduct of Research. The program includes 30 training faculty divided into four primary axes: Endocrinology, Bone Cell Biology, Musculoskeletal Cancer, and Mechanobiology and Mechanics. Each of these have three separate focus groups, and all trainees are required to have mentors from more than one of these training pods. The training program description includes a list of activities for the trainees, requirements for the mentors, didactic and career development programs, as well as assessment programs for the trainees, mentors, and the overall training program.