Biostatistics

项目总结 生物统计共享资源(B-SR)人员在所有七个项目中与SCI成员合作 支持所有阶段的研究，从人口和基础科学到转化研究到临床试验 和有效性研究。能力与SCI成员的需求相匹配，提供全方位的 生物统计学和研究设计专业知识，从标准技术到专门开发的创新方法 加强基础科学、翻译科学、临床科学和人口科学的研究。自上次审查以来， 根据SCI成员的反馈，将原有的生物统计与信息学共享资源分为两部分 2017年的单独资源(经EAB和NCI批准)：(1)B-SR和(2)共享的生物医学信息学 资源(BI-SR)。虽然这两个资源继续具有协同效应，但这一变化允许更深层次的关注 在每个SR的单独任务中。新的BI-SR侧重于数据组织、管理、管理和 支持这些研究的采矿。B-SR的优势在于研究设计和结果分析，重点是 从统计学上讲，这是一种可靠的方法。B-SR在议定书审查和监测中也发挥着关键作用 委员会和临床试验科学审查委员会。所有计划的成员经常使用B- SR，其中使用最多的是人口科学和癌症治疗计划。B-SR 在当前筹资期间参与了82份以癌症为重点的出版物，其中16份是高影响力出版物 出版物。B-SR的年度预算是261,592美元，而CCSG的请求是149,916美元。因此， B-SR寻求CCSG基金57%的支持。

PROJECT SUMMARY The Biostatistics Shared Resource (B-SR) personnel collaborate with SCI members in all seven programs and support all phases of research, from population and basic sciences through translational studies to clinical trials and effectiveness research. Capabilities are matched to the needs of SCI members, providing a full range of biostatistics and study design expertise, from standard techniques to innovative methods developed specifically to enhance the basic, translational, clinical, and population sciences research efforts. Since the last review and based on SCI member feedback, the former Biostatistics and Informatics Shared Resource was divided into two separate resources in 2017 (with EAB and NCI approval): (1) the B-SR and (2) the Biomedical Informatics Shared Resource (BI-SR). While the two resources continue to have synergy, the change has allowed for a deeper focus on each SR’s individual missions. The new BI-SR focuses on data organization, curation, management, and mining that supports the studies. The B-SR strengths are study design and results analysis, with emphasis on statistically sound methodology. The B-SR also plays a key role in the Protocol Review and Monitoring Committee and the Clinical Trials Scientific Review Committee. Members of all programs regularly use the B- SR, with the heaviest use coming from the Population Sciences and Cancer Therapeutics programs. The B-SR participated in 82 cancer-focused publications in the current funding period, 16 of them in high-impact publications. The annual budget of the B-SR is $261,592, yet the CCSG request is $149,916. Accordingly, the B-SR seeks 57% of its support from CCSG funds.