Cancer Research Center of Hawaii

描述（由申请人提供）：夏威夷癌症研究中心（CRCH）是nci指定的临床癌症中心。CRCH在癌症研究、教育、社区外展和患者护理方面负有多种责任。它是夏威夷州唯一这样的机构。夏威夷为癌症提供了特殊的研究机会，这在美国或世界其他地方是无与伦比的。夏威夷独特的研究机会的基础是该州人口的种族和文化多样性，以及其地理位置和独特的环境。CRCH的研究工作分为三个研究项目：癌症病因学、预防和控制、天然产物和癌症生物学。所有这三个研究项目都充分利用了夏威夷多种族人口所提供的生物多样性，进行基础研究、以人口为基础的研究和临床研究，以及利用热带生物圈的自然多样性进行药物发现。在当前的CCSG资助周期内，这三个项目都取得了重大的科学进展。从1999年至今，在国际文献的800多份出版物中获得了令人兴奋和新颖的研究成果。CRCH还经营夏威夷肿瘤登记处，全国12个SEER登记处之一，癌症信息服务-太平洋，以及一个大型临床试验单位，为夏威夷的癌症患者提供大约150个临床试验。在目前的CCSG支援周期内，CRCH的研究空间约增加了一倍，包括将于2005年年中落成的新研究大楼内约50,000平方英尺的空间。此外，正在计划建造一座约35万平方英尺的新癌症中心大楼，它不仅将为当前的研究项目提供扩展的设施，还将包括一个现代化的门诊护理设施，与该州最大的医院合作，提供全面的癌症护理服务。这些发展将有助于在未来建立一个强大的临床研究活动。

DESCRIPTION (provided by applicant): The Cancer Research Center of Hawaii (CRCH) is an NCI-designated Clinical Cancer Center. CRCH has diverse responsibility in cancer research, education, community outreach, and patient care. It is the only such institution in the State of Hawaii. Hawaii offers special research opportunities for cancer that are unparalleled elsewhere in the country or the world. The basis for the unique research opportunities in Hawaii are the ethnic and cultural variety of the State's population as well as its geographic location and unique environment. Research efforts at CRCH are organized into three research programs: Cancer Etiology, Prevention and Control, and Natural Products and Cancer Biology. All three research programs take particular advantage of the biodiversity offered by the multiethnic population of Hawaii for basic, population-based, and clinical studies as well as by the natural diversity of the tropical biosphere for drug discovery. All three programs have made significant scientific progress during the current CCSG funding cycle. Exciting and novel research results have been obtained and disseminated in over 800 publications in the international literature from 1999 until today. CRCH also operates the Hawaii Tumor Registry, one of 12 SEER registries in the country, the Cancer Information Service-Pacific, and a large Clinical Trials Unit which makes approximately 150 clinical trials available to Hawaii's cancer patients. Over the current cycle of CCSG support research space at CRCH approximately doubled, including approximately 50,000 square feet in a new research building to be completed by mid-2005. Furthermore, plans are underway to construct a new Cancer Center building of approximately 350,000 square feet which will not only provide expanded facilities for current research programs, but will include a modern outpatient care facility offering comprehensive cancer care services in partnership with the largest hospitals in the State. These developments will allow to build a strong clinical research activity in the future.