Using Methods in Genetic Epidemiology to Elucidate the Relationship Between Viral Infection and Risk of Autoimmune Disease
Using Methods in Genetic Epidemiology to Elucidate the Relationship Between Viral Infection and Risk of Autoimmune Disease
批准号:
nhmrc : 1125141
负责人:
A/Pr John Miles
金额:
$42.47万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2020-12-31
中文摘要
当身体的自然防御机制错误地攻击健康组织时,就会发生自身免疫性疾病。长期以来,人们一直认为病毒感染可能在引发自身免疫性疾病方面发挥作用。我们的研究旨在发现影响身体对病毒感染反应的基因,以及随后是否相同的基因参与自身免疫性疾病的病理学。如果相同的基因在两种情况下都很重要,那么这将提供病毒引发自身免疫性疾病的证据。
英文摘要
Autoimmune diseases occur when the body's natural defense mechanisms attack healthy tissues by mistake. It has long been thought that viral infections might play a role in triggering autoimmune disease. Our study aims to find genes that influence the body's response to viral infection and subsequently whether the same genes are involved in autoimmune disease pathology. If the same genes are important in both situations then this will provide evidence that viruses trigger autoimmune disease.
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会议论文
Understanding and modulating the human immune system
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批准号:nhmrc : GNT1131732
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项目类别:Career Development Fellowships
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资助金额:$47.01万
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财政年份:2017
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负责人:A/Pr John Miles
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依托单位:
Using Methods in Genetic Epidemiology to Elucidate the Relationship Between Viral Infection and Risk of Autoimmune Disease
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批准号:nhmrc : GNT1125141
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项目类别:Project Grants
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资助金额:$62.24万
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财政年份:2017
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负责人:A/Pr John Miles
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依托单位:
Understanding and modulating the human immune system
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批准号:nhmrc : 1131732
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项目类别:Career Development Fellowships
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资助金额:$32.12万
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财政年份:2017
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负责人:A/Pr John Miles
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依托单位:
Defining the molecular and functional features of protective HIV-specific T cells
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批准号:nhmrc : 1106756
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项目类别:Project Grants
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资助金额:$40.59万
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财政年份:2016
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负责人:A/Pr John Miles
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依托单位:
Defining the molecular and functional features of protective HIV-specific T cells
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批准号:nhmrc : GNT1106756
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项目类别:Project Grants
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资助金额:$59.2万
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财政年份:2016
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负责人:A/Pr John Miles
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依托单位:
A new approach to the design and evaluation of T cell vaccines for cancer and infectious disease.
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批准号:nhmrc : 1078987
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项目类别:Project Grants
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资助金额:$26.28万
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财政年份:2015
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负责人:A/Pr John Miles
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依托单位:
Development of CD96 antibodies for cancer treatment
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批准号:nhmrc : 1093566
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项目类别:Development Grants
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资助金额:$54.73万
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财政年份:2015
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负责人:A/Pr John Miles
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依托单位:
Tracking the human immune system over years of life
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批准号:nhmrc : GNT1069281
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项目类别:Project Grants
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资助金额:$45.64万
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财政年份:2014
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负责人:A/Pr John Miles
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依托单位:
Determining the biological significance of allelic sequence variation within the T cell receptor loci
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批准号:nhmrc : 1067374
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项目类别:Project Grants
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资助金额:$41.85万
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财政年份:2014
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负责人:A/Pr John Miles
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依托单位:
Following the T cell repertoire over the human life course
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批准号:nhmrc : 1069281
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项目类别:Project Grants
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资助金额:$31.55万
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财政年份:2014
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负责人:A/Pr John Miles
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依托单位:
Tracking the impact of superinfection with a common Herpesvirus on T cell immunity in humans
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批准号:nhmrc : 1045870
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项目类别:Project Grants
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资助金额:$21.19万
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财政年份:2013
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负责人:A/Pr John Miles
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依托单位:
Investigations into supraphysiologic T cell receptors and T cell agonists.
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批准号:nhmrc : 1031652
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项目类别:Career Development Fellowships
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资助金额:$27.23万
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财政年份:2012
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负责人:A/Pr John Miles
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依托单位:
The role of long peptide epitopes in antiviral CD8+ T cell recognition.
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批准号:nhmrc : 1021620
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项目类别:Project Grants
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资助金额:$28.98万
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财政年份:2012
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负责人:A/Pr John Miles
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依托单位:
Investigations into the biology and functionality of the human T cell receptor
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批准号:nhmrc : 613664
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项目类别:NHMRC Project Grants
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资助金额:$28.29万
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财政年份:2010
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负责人:A/Pr John Miles
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依托单位:
Investigations into the architectural and biophysical features of optimal T cell receptor design
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批准号:nhmrc : 496721
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项目类别:Early Career Fellowships
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资助金额:$16.8万
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财政年份:2008
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负责人:A/Pr John Miles
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依托单位:
Investigations into the cytolytic T cell response during Epstein-Barr virus related disease
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批准号:nhmrc : 389937
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项目类别:NHMRC Postgraduate Scholarships
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资助金额:$0.25万
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财政年份:2006
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负责人:A/Pr John Miles
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依托单位:
Cytotoxic T lymphocyte response to Epstein-Barr virus
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批准号:nhmrc : 339480
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项目类别:NHMRC Postgraduate Scholarships
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资助金额:$2.81万
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财政年份:2005
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负责人:A/Pr John Miles
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依托单位:
国内基金
海外基金
Computational Methods for Analyzing Toponome Data
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批准号:60601030
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项目类别:青年科学基金项目
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资助金额:17.0万元
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批准年份:2006
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负责人:Axel Mosig
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依托单位: