The Dynamic Control of Chromatin Structure
The Dynamic Control of Chromatin Structure
批准号:
DP0774014
负责人:
Prof David Tremethick
金额:
$18.25万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2007
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2007-01-01 至 2010-12-31
中文摘要
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英文摘要
A human chromosome is a highly heterogeneous global structure because along its axis, it folds to different extents to form either highly compacted domains that repress the expression of genes or less condensed regions that enable genes to be turned on. Changes to the structure or stability of chromosomes, and the corresponding alterations to gene expression, have been linked to many diseases states like defects in human development and cancer. This study will uncover the underpinning mechanism of how our chromosomes are organised into distinct functional domains, which may offer the potential to develop new strategies to correct chromosomal abnormalities.
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国内基金
海外基金
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批准号:--
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项目类别:--
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资助金额:25万元
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批准年份:2020
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依托单位: