Bone tissue engineering using dental pulp cells cultured without osteogenic differentiation induction.
Bone tissue engineering using dental pulp cells cultured without osteogenic differentiation induction.
批准号:
21592515
负责人:
YAMAGUCHI Satoshi
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
In a common strategy of bone tissue engineering, stem cells are differentiated into osteoblastic cells using differentiation-inducing agents. This study showed that human dental pulp cells cultured without osteogenic differentiation induction possessed the capacity to generate bone tissues in vivo. Furthermore, human dental pulp cells expanded in serum-free condition formed bone-like tissues in vivo. These results lead to set up a simple and safety strategy of bone tissue engineering like not previous.
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In vivo formation by human dental pulp cells cultured without cell sorting and osteogenic differentiation induction
无需细胞分选和成骨分化诱导培养的人牙髓细胞的体内形成
DOI:
--
发表时间:
2009
期刊:
Journal of Oral Tissue Engineering
影响因子:
--
作者:
[Hamada K., Yamaguchi S., Abe S., Ichinose S., Abe T., Yamashita Y., Amagasa T.]
通讯作者:
Amagasa T.
DOI:
10.1186/scrt43
发表时间:
2011-01-20
期刊:
Stem cell research & therapy
影响因子:
7.5
作者:
[Abe S, Hamada K, Yamaguchi S, Amagasa T, Miura M]
通讯作者:
Miura M
分化誘導因子を必要としないヒト歯髄組織由来細胞による骨組織形成
使用人牙髓组织来源的细胞形成骨组织,无需分化诱导因子
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[山口聰, 阿部成宏, 濱田啓一, 天笠光雄]
通讯作者:
天笠光雄
DOI:
10.1177/0022034509338253
发表时间:
2009-06-01
期刊:
JOURNAL OF DENTAL RESEARCH
影响因子:
7.6
作者:
[Shigeishi, H., Yamaguchi, S., Kamata, N.]
通讯作者:
Kamata, N.
放射線による歯根形成阻害メカニズム
辐射抑制牙根形成的机制
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[阿部成宏, 山口聰, 濱田啓一, 天笠光雄]
通讯作者:
天笠光雄
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