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Development of the novel molecular targeted therapy against hepatocellular carcinoma invasion and metastasis

Development of the novel molecular targeted therapy against hepatocellular carcinoma invasion and metastasis
新型抗肝细胞癌侵袭转移分子靶向治疗药物的研究进展
批准号:
21791288
负责人:
KOBAYASHI Tsuyoshi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
翻译
本研究旨在开发抗肝细胞癌侵袭转移的新型分子靶向治疗方法。虽然我们还不能明确h-prune在肝细胞癌中的表达的临床意义,但我们阐明了h-prune在甲状腺癌中频繁表达,并在间变性甲状腺癌细胞的侵袭和转移中起着重要作用。
英文摘要
The aim of this study was to develop the novel molecular targeted therapy against hepatocellular carcinoma invasion and metastasis. Although we were not able to clarify the clinical significance of expression of h-prune in hepatocellular carcinoma, we elucidated that h-prune frequently expressed in thyroid cancers and had an essential role in anaplastic thyroid cancer cell invasion and metastasis.
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DOI: 10.1016/j.jhep.2011.04.029
发表时间: 2012-01-01
期刊: JOURNAL OF HEPATOLOGY
影响因子: 25.7
作者: [Kuroda, Shintaro, Tashiro, Hirotaka, Ohdan, Hideki]
通讯作者: Ohdan, Hideki
DOI: 10.1007/s00534-011-0379-4
发表时间: 2011-03
期刊: Journal of Hepato-Biliary-Pancreatic Sciences
影响因子: 3
作者: [Tsuyoshi Kobayashi;T. Itamoto;H. Tashiro;H. Amano;A. Oshita;Yoshisato Tanimoto;S. Kuroda;H. Tazawa;H. Ohdan]
通讯作者: Tsuyoshi Kobayashi;T. Itamoto;H. Tashiro;H. Amano;A. Oshita;Yoshisato Tanimoto;S. Kuroda;H. Tazawa;H. Ohdan
DOI: 10.1007/s00268-010-0929-y
发表时间: 2011-04
期刊: World Journal of Surgery
影响因子: 2.6
作者: [S. Kuroda;H. Tashiro;Tsuyoshi Kobayashi;A. Oshita;H. Amano;H. Ohdan]
通讯作者: S. Kuroda;H. Tashiro;Tsuyoshi Kobayashi;A. Oshita;H. Amano;H. Ohdan
肝細胞癌に対する肝中央二区域切除
中央肝双段切除术治疗肝细胞癌
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [楠部潤子, 小林剛, 田代裕尊, 杉野圭三, 嶋本文雄, 大段秀樹, 小林剛]
通讯作者: 小林剛
14
    On developments and applications of Heegaard theory
    • 批准号:
      21540082
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.16万
    • 财政年份:
      2009
    • 负责人:
      KOBAYASHI Tsuyoshi
    • 依托单位:
    Research on 3-manifolds based on geometric techniques and its expanse
    • 批准号:
      19540083
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.25万
    • 财政年份:
      2007
    • 负责人:
      KOBAYASHI Tsuyoshi
    • 依托单位:
    Geometric structures of 3-manifolds and various related structures
    • 批准号:
      17540077
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.41万
    • 财政年份:
      2005
    • 负责人:
      KOBAYASHI Tsuyoshi
    • 依托单位:
    Research on various geometric structures on 3-manifolds
    • 批准号:
      15540073
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.34万
    • 财政年份:
      2003
    • 负责人:
      KOBAYASHI Tsuyoshi
    • 依托单位:
    海外基金