INVESTIGATION OF STEM CELL METABOLISM BY NMR

通过核磁共振研究干细胞代谢

• 批准号: 8168896
• 负责人: JOHN GLUSHKA
• 金额: $ 0.17万
• 依托单位: UNIVERSITY OF GEORGIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-10 至 2011-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168896
• 关键词: Affect; Cells; Computer Retrieval of Information on Scientific Projects Database; Funding; Glucose; Grant; Growth; Institution; Investigation; Label; Metabolism; Research; Research Personnel; Resources; Source; Staging; Stem cells; United States National Institutes of Health; cell type

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The utilization of pluripotent cells to form specific cell types requires an understanding of basic metabolism and the factors that affect differentiation. In this study, stem cells are being grown with 13C isotopically labeled substrates such as glucose, and the products of the metabolism are identified by NMR. Cells at different stages of growth and under different conditions are being examined.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 多能细胞形成特定细胞类型的利用需要了解基本代谢和影响分化的因素。 在这项研究中，干细胞在同位素标记的底物（如葡萄糖）中生长，并通过NMR鉴定代谢产物。 在不同的生长阶段和不同条件下的细胞正在研究。