INVESTIGATION OF STEM CELL METABOLISM BY NMR

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 利用多能细胞形成特定的细胞类型需要了解基本代谢和影响分化的因素。 在这项研究中，干细胞在13 C 同位素标记的底物如葡萄糖和代谢产物通过NMR鉴定。 正在检查处于不同生长阶段和不同条件下的细胞。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The utilization of pluripotent cells to form specific cell types requires an understanding of basic metabolism and the factors that affect differentiation. In this study, stem cells are being grown with 13C isotopically labeled substrates such as glucose, and the products of the metabolism are identified by NMR. Cells at different stages of growth and under different conditions are being examined.