INVESTIGATION OF STEM CELL METABOLISM BY NMR

通过核磁共振研究干细胞代谢

• 批准号: 8361816
• 负责人: JOHN GLUSHKA
• 金额: $ 0.18万
• 依托单位: UNIVERSITY OF GEORGIA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-02-01 至 2012-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361816
• 关键词: Affect; Cells; Funding; Glucose; Grant; Growth; Investigation; Label; Metabolism; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Source; Staging; Stem cells; United States National Institutes of Health; cell type; cost

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The utilization of pluripotent cells to form specific cell types requires an understanding of basic metabolism and the factors that affect differentiation. In this study, stem cells are being grown with 13Cisotopically labeled substrates such as glucose, and the products of the metabolism are identified by NMR. Cells at different stages of growth and under different conditions are being examined.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 多能细胞形成特定细胞类型的利用需要了解基本代谢和影响分化的因素。 在这项研究中，干细胞在同位素标记的底物（如葡萄糖）中生长，并通过NMR鉴定代谢产物。 在不同的生长阶段和不同条件下的细胞正在研究。