SEARCH FOR DIABETES IN YOUTH

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The second five-year phase of SEARCH will address the following specific research aims: AIM 1: Prospectively ascertain newly diagnosed (2006 - 2009) incident diabetes cases in youth less than 20 years of age, and collect data that permits estimation of temporal trends in diabetes incidence by age, gender, race/ethnicity, and diabetes type for the period 2002-2008; AIM 2: Conduct longitudinal follow-up of 2002 - 2005 incident cases already recruited to SEARCH in order to document the evolution of newly diagnosed diabetes according to clinical and biochemical factors and characterize the evolution of key risk factors for diabetes complications, according to diabetes type and race/ethnicity; AIM 3: Assess the impact of quality of diabetes care in youth on short- and long-term outcomes including quality of life by: completing analytic work initiated in SEARCH as described in the Quality of Care Roadmap and expanding the scope of quality of care assessment in order to explore the interrelationships of patient characteristics with important domains of health care outcomes, such as glycemic control, satisfaction with care, receipt of recommended services, complications, and quality of life; and AIM 4: Develop and validate simple and low-cost case definitions and classifications of diabetes types in youth that can be used for public health surveillance.