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中文摘要
翻译
该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者(PI)可能从另一个NIH来源获得主要资金, 因此可以在其他CRISP条目中表示。列出的机构是 中心,不一定是研究者的机构。 第二个五年期的研究将致力于以下具体的研究目标:目标1:(2006 - 2009年)20岁以下青年的糖尿病发病病例,并收集数据,以估计2002-2008年期间按年龄、性别、种族/民族和糖尿病类型划分的糖尿病发病率的时间趋势; AIM 2:对2002 - 2005年已招募到糖尿病研究中心的事件病例进行纵向随访,以根据临床和生化因素记录新诊断糖尿病的演变,并根据糖尿病类型和种族/民族描述糖尿病并发症关键风险因素的演变;目的3:通过以下方式评估青年糖尿病护理质量对短期和长期结果(包括生活质量)的影响:完成护理质量路线图中所述的护理质量评估的分析工作,并扩大护理质量评估的范围,以探索患者特征与医疗保健结果的重要领域(例如血糖控制、护理满意度、接受推荐服务、并发症和生活质量)的相互关系;和AIM 4:开发和验证简单且低成本的病例定义和分类青年糖尿病类型可用于公共卫生监测。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The second five-year phase of SEARCH will address the following specific research aims: AIM 1: Prospectively ascertain newly diagnosed (2006 - 2009) incident diabetes cases in youth less than 20 years of age, and collect data that permits estimation of temporal trends in diabetes incidence by age, gender, race/ethnicity, and diabetes type for the period 2002-2008; AIM 2: Conduct longitudinal follow-up of 2002 - 2005 incident cases already recruited to SEARCH in order to document the evolution of newly diagnosed diabetes according to clinical and biochemical factors and characterize the evolution of key risk factors for diabetes complications, according to diabetes type and race/ethnicity; AIM 3: Assess the impact of quality of diabetes care in youth on short- and long-term outcomes including quality of life by: completing analytic work initiated in SEARCH as described in the Quality of Care Roadmap and expanding the scope of quality of care assessment in order to explore the interrelationships of patient characteristics with important domains of health care outcomes, such as glycemic control, satisfaction with care, receipt of recommended services, complications, and quality of life; and AIM 4: Develop and validate simple and low-cost case definitions and classifications of diabetes types in youth that can be used for public health surveillance.
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会议论文
SEARCH for Diabetes in Youth Registry Study, Phase 4: Washington Center
  • 批准号:
    9041835
  • 项目类别:
  • 资助金额:
    $38.0万
  • 财政年份:
    2015
  • 负责人:
    Catherine Pihoker
  • 依托单位:
SEARCH for Diabetes in Youth Registry Study, Phase 4: Washington Center
  • 批准号:
    9332119
  • 项目类别:
  • 资助金额:
    $37.62万
  • 财政年份:
    2015
  • 负责人:
    Catherine Pihoker
  • 依托单位:
SEARCH for Diabetes in Youth Registry Study, Phase 4: Washington Center
  • 批准号:
    9127727
  • 项目类别:
  • 资助金额:
    $37.74万
  • 财政年份:
    2015
  • 负责人:
    Catherine Pihoker
  • 依托单位:
SEARCH for Diabetes in Youth Registry Study, Phase 4: Washington Center
  • 批准号:
    9753810
  • 项目类别:
  • 资助金额:
    $37.59万
  • 财政年份:
    2015
  • 负责人:
    Catherine Pihoker
  • 依托单位:
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: