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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金, 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 第二个五年搜索阶段将针对以下具体研究目标:目标1:前瞻性地确定20岁以下青年中新诊断的(2006-2009年)糖尿病事件病例,并收集数据,以便能够按年龄、性别、种族/族裔和糖尿病类型估计2002-2008年期间糖尿病发病率的时间趋势;目标2:对已招募用于搜索的2002-2005年事件病例进行纵向跟踪,以便根据临床和生化因素记录新诊断糖尿病的演变,并根据糖尿病类型和种族/族裔描述糖尿病并发症的关键风险因素的演变;目的3:评估青年糖尿病护理质量对包括生活质量在内的短期和长期结果的影响:按照护理质量路线图的描述完成在搜索中启动的分析工作,并扩大护理质量评估的范围,以探索患者特征与保健结果的重要领域之间的相互关系,如血糖控制、护理满意度、接受推荐服务、并发症和生活质量;以及目标4:制定和验证可用于公共卫生监测的简单和低成本的青年糖尿病类型的病例定义和分类。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The second five-year phase of SEARCH will address the following specific research aims: AIM 1: Prospectively ascertain newly diagnosed (2006 - 2009) incident diabetes cases in youth less than 20 years of age, and collect data that permits estimation of temporal trends in diabetes incidence by age, gender, race/ethnicity, and diabetes type for the period 2002-2008; AIM 2: Conduct longitudinal follow-up of 2002 - 2005 incident cases already recruited to SEARCH in order to document the evolution of newly diagnosed diabetes according to clinical and biochemical factors and characterize the evolution of key risk factors for diabetes complications, according to diabetes type and race/ethnicity; AIM 3: Assess the impact of quality of diabetes care in youth on short- and long-term outcomes including quality of life by: completing analytic work initiated in SEARCH as described in the Quality of Care Roadmap and expanding the scope of quality of care assessment in order to explore the interrelationships of patient characteristics with important domains of health care outcomes, such as glycemic control, satisfaction with care, receipt of recommended services, complications, and quality of life; and AIM 4: Develop and validate simple and low-cost case definitions and classifications of diabetes types in youth that can be used for public health surveillance.
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会议论文
SEARCH for Diabetes in Youth Registry Study, Phase 4: Washington Center
  • 批准号:
    9041835
  • 项目类别:
  • 资助金额:
    $38.0万
  • 财政年份:
    2015
  • 负责人:
    Catherine Pihoker
  • 依托单位:
SEARCH for Diabetes in Youth Registry Study, Phase 4: Washington Center
  • 批准号:
    9332119
  • 项目类别:
  • 资助金额:
    $37.62万
  • 财政年份:
    2015
  • 负责人:
    Catherine Pihoker
  • 依托单位:
SEARCH for Diabetes in Youth Registry Study, Phase 4: Washington Center
  • 批准号:
    9127727
  • 项目类别:
  • 资助金额:
    $37.74万
  • 财政年份:
    2015
  • 负责人:
    Catherine Pihoker
  • 依托单位:
SEARCH for Diabetes in Youth Registry Study, Phase 4: Washington Center
  • 批准号:
    9753810
  • 项目类别:
  • 资助金额:
    $37.59万
  • 财政年份:
    2015
  • 负责人:
    Catherine Pihoker
  • 依托单位:
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: