Developmental Research Program

发展研究计划

• 批准号: 10601409
• 负责人: ULRIKE PETERS
• 金额: $ 4.74万
• 依托单位: FRED HUTCHINSON CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10601409
• 关键词: Developmental; Research; Program

Project Summary/Abstract of the Development Research Program The Developmental Research Program (DRP) will provide key support to develop novel translational early-phase Projects in the area of cancer disparities that, ultimately, will contribute to the reduction in the morbidity and mortality of cancer among medically underserved populations. In line with the overall goals of our Translational Research Program in Colorectal Cancer Disparities. The DRP will foster new collaborations between participating institutions and initiate collaborations with other SPOREs and Disparities P20’s. Additionally, our Career Enhancement Program (operated through our Administrative Core) will encourage early career investigators, particularly those from racially/ethnically diverse backgrounds, to apply to the DRP. Our goal is to fund Developmental Research Projects encompassing a range of translational cancer disparities research, including molecular biology, epidemiology (primary and secondary prevention), early detection, prognosis, therapeutics, and survivorship. To achieve this goal, we will identify promising translational cancer disparities Research Projects through broad solicitation (Aim 1). We will encourage early and senior investigators to collaborate across multiple disciplines. New ideas will be solicited on an annual basis by broadly advertising pilot funding and targeted engagement with promising faculty. Aim 2 will focus on rigorous and balanced scientific review of DRP proposals. We will convene an expert panel encompassing a broad range of scientific disciplines and also include participation from our Community Advisory Board. We will follow the National Institutes of Health SPORE guidelines for these reviews. In addition to financial support, funded DRP Projects will receive strong infrastructure support and access to biospecimens and expertise related to novel technologies through our Administrative and Biospecimen and Pathology Cores (Aim 3). With our generous institutional matching support we will award $100,000 of funding to DRP projects annually and anticipate that each year we will fund about 3 one-year projects. The progress of all DRP projects will be monitored regularly with respect to achieving their specific aims and milestones using clearly defined evaluation criteria (Aim 4). Of particular interest will be the potential of each project to advance to a full SPORE Project. We will also track long-term reportable outcomes of each project such as peer-reviewed manuscripts, oral presentations and grant funding.

开发研究计划的项目摘要/摘要 发展研究计划(DRP)将为开发新的翻译技术提供关键支持 癌症差异领域的早期项目，最终将有助于减少 医疗服务不足人群中的癌症发病率和死亡率。与以下总体目标相一致 我们的结直肠癌差异转化研究计划。DRP将促进新的合作 参与机构之间，并发起与其他孢子的合作和差距P20‘S。 此外，我们的职业提升计划(通过我们的行政核心运作)将鼓励 早期职业调查员，特别是来自种族/族裔背景不同的人，申请DRP。 我们的目标是资助包含一系列癌症翻译差异的发展研究项目 研究，包括分子生物学、流行病学(一级和二级预防)、早期发现、 预后、治疗和生存。为了实现这一目标，我们将发现有希望的转化性癌症 通过广泛征集开展差异研究项目(目标1)。我们将鼓励提早和提早 调查人员可以跨多个学科进行协作。将每年征集新的想法，由 广泛地宣传试点资金和与有前途的教师的有针对性的接触。目标2将专注于严格的 对DRP提案进行平衡的科学审查。我们将召集一个专家小组，由一个广泛的 科学学科的范围，还包括我们的社区咨询委员会的参与。我们会跟随 美国国立卫生研究院的孢子指南为这些审查。除了资金支持外，还资助了 DRP项目将得到强有力的基础设施支持，并获得与以下方面有关的生物武器和专门知识 通过我们的行政、生物医学和病理学核心提供新技术(目标3)。带着我们的 慷慨的机构匹配支持我们每年将向DRP项目提供10万美元的资金，并 预计每年我们将资助约3个为期一年的项目。所有DRP项目的进度将是 定期监测其具体目标和里程碑的实现情况，并使用明确定义的 评价标准(目标4)。令人特别感兴趣的将是每个项目发展到完全孢子的潜力。 项目。我们还将跟踪每个项目的长期可报告成果，如同行评审的手稿， 口头陈述和赠款资助。