Program in Membrane Interface Biology
Program in Membrane Interface Biology
批准号:
nhmrc : 1037320
负责人:
Prof Alpha Yap
金额:
$498.05万
依托单位国家:
澳大利亚
项目类别:
Program Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2017-12-31
中文摘要
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英文摘要
This research program aims to gain a detailed understanding of the organisation of the cell surface at the molecular level. The cell surface is organised into domains with distinct functions. Visualisation of these domains, identifying their important components, and understanding how they form and function will have huge importance for therapeutic strategies aimed at combatting the changes associated with cell transformation in cancer and in other human diseases such as muscular dystrophy.
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会议论文
Forces in Nature: Tissue mechanics and cell sociology
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批准号:FL230100100
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项目类别:Australian Laureate Fellowships
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资助金额:$226.26万
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财政年份:2024
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负责人:Prof Alpha Yap
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依托单位:
Keeping forces local for epithelial homeostasis
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批准号:DP220103951
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项目类别:Discovery Projects
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资助金额:$41.1万
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财政年份:2022
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负责人:Prof Alpha Yap
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依托单位:
RhoA signaling: the nanoscale mechanisms of mechanochemical regulation
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批准号:DP190102871
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项目类别:Discovery Projects
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资助金额:$52.78万
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财政年份:2019
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负责人:Prof Alpha Yap
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依托单位:
How caveolae condition tissue mechanics for an anti-tumor niche.
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批准号:nhmrc : 1140090
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项目类别:Project Grants
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资助金额:$73.78万
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财政年份:2018
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负责人:Prof Alpha Yap
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依托单位:
Mechanobiology of epithelial homeostasis in health and disease
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批准号:nhmrc : GNT1136592
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项目类别:Research Fellowships
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资助金额:$87.6万
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财政年份:2018
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负责人:Prof Alpha Yap
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依托单位:
How caveolae condition tissue mechanics for an anti-tumor niche.
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批准号:nhmrc : GNT1140090
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项目类别:Project Grants
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资助金额:$109.12万
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财政年份:2018
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负责人:Prof Alpha Yap
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依托单位:
Mechanobiology of epithelial homeostasis in health and disease
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批准号:nhmrc : 1136592
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项目类别:Research Fellowships
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资助金额:$59.23万
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财政年份:2018
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负责人:Prof Alpha Yap
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依托单位:
A mechanotransduction apparatus to coordinate epithelial collective cell migration.
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批准号:nhmrc : 1123816
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项目类别:Project Grants
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资助金额:$67.95万
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财政年份:2017
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负责人:Prof Alpha Yap
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依托单位:
Tissue tension homeostasis by junctional mechanosensing.
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批准号:DP150101367
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项目类别:Discovery Projects
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资助金额:$31.22万
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财政年份:2015
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负责人:Prof Alpha Yap
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依托单位:
Cadherin Biology in Morphogenesis and Disease
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批准号:nhmrc : 1044041
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项目类别:Research Fellowships
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资助金额:$50.13万
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财政年份:2013
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负责人:Prof Alpha Yap
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依托单位:
The Plasma membrane in health and disease
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批准号:nhmrc : GNT1037320
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项目类别:Programs
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资助金额:$473.47万
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财政年份:2013
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负责人:Prof Alpha Yap
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依托单位:
Mechanotransduction: a new paradigm for cadherin junction biology
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批准号:DP120104667
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项目类别:Discovery Projects
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资助金额:$25.78万
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财政年份:2012
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负责人:Prof Alpha Yap
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依托单位:
Cortactin: integrating cadherin signalling for junctional integrity
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批准号:nhmrc : 1010489
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项目类别:NHMRC Project Grants
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资助金额:$39.6万
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财政年份:2011
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负责人:Prof Alpha Yap
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 631383
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项目类别:NHMRC Research Fellowships
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资助金额:$25.67万
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财政年份:2010
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负责人:Prof Alpha Yap
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依托单位:
Myosin VI: a novel molecular apparatus for epithelial cohesion
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批准号:nhmrc : 631377
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项目类别:NHMRC Project Grants
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资助金额:$40.35万
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财政年份:2010
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负责人:Prof Alpha Yap
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依托单位:
Actin cytoskeleton regulation by E-cadherin and Src.
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批准号:DP0988935
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项目类别:Discovery Projects
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资助金额:$20.8万
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财政年份:2009
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负责人:Prof Alpha Yap
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依托单位:
Regulation of Myosin II by E-cadherin adhesion.
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批准号:nhmrc : 511155
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项目类别:NHMRC Project Grants
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资助金额:$38.24万
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财政年份:2008
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负责人:Prof Alpha Yap
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依托单位:
Preserving barriers: how cadherin signaling coordinates dynamic adhesion and tight junction assembly in epithelial cell.
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批准号:nhmrc : 511156
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项目类别:NHMRC Project Grants
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资助金额:$37.2万
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财政年份:2008
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负责人:Prof Alpha Yap
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依托单位:
Regulation of dynamic cell-cell adhesions by coordinated action of lipid kinases and phosphatases
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批准号:nhmrc : 455824
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项目类别:NHMRC Project Grants
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资助金额:$35.31万
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财政年份:2007
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负责人:Prof Alpha Yap
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依托单位:
Balancing cadherin-actin cooperation: the key regulatory role of Ena/VASP proteins
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批准号:DP0664395
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项目类别:Discovery Projects
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资助金额:$17.6万
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财政年份:2006
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负责人:Prof Alpha Yap
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依托单位:
海外基金