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Forces in Nature: Tissue mechanics and cell sociology

Forces in Nature: Tissue mechanics and cell sociology
自然力量：组织力学和细胞社会学
批准号：
FL230100100
负责人：
Prof Alpha Yap
金额：
$226.26万
依托单位：
The University of Queensland
依托单位国家：
澳大利亚
项目类别：
Australian Laureate Fellowships
财政年份：
2024
资助国家：
澳大利亚
项目状态：
未结题
起止时间：
2024-01-01 至 2028-12-31
来源：
https://dataportal.arc.gov.au/RGS/Web/Grants/FL230100100
关键词：
ForcesNatureTissuemechanicscell

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中文摘要
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英文摘要
Epithelial cells cover surfaces in the body, forming a shield to protect us from the environment. Despite their importance, we understand poorly how the cells communicate. This project aims to test the novel concept that epithelial cells communicate via transmission and detection of mechanical forces, using an innovative combination of cellular and biophysical experiments and physical theory. The expected outcomes are new knowledge, interdisciplinary training for young scientists, new national research capacity and growing international collaborations. Benefits include enhancing Australia’s scientific linkages and research capacity and providing fundamental knowledge that could lead to future advances in bioengineering and drug discovery.
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Keeping forces local for epithelial homeostasis
  • 批准号：
    DP220103951
  • 项目类别：
    Discovery Projects
  • 资助金额：
    $41.1万
  • 财政年份：
    2022
  • 负责人：
    Prof Alpha Yap
  • 依托单位：
    The University of Queensland
RhoA signaling: the nanoscale mechanisms of mechanochemical regulation
  • 批准号：
    DP190102871
  • 项目类别：
    Discovery Projects
  • 资助金额：
    $52.78万
  • 财政年份：
    2019
  • 负责人：
    Prof Alpha Yap
  • 依托单位：
    The University of Queensland
How caveolae condition tissue mechanics for an anti-tumor niche.
  • 批准号：
    nhmrc : 1140090
  • 项目类别：
    Project Grants
  • 资助金额：
    $73.78万
  • 财政年份：
    2018
  • 负责人：
    Prof Alpha Yap
  • 依托单位：
    The University of Queensland
Mechanobiology of epithelial homeostasis in health and disease
  • 批准号：
    nhmrc : GNT1136592
  • 项目类别：
    Research Fellowships
  • 资助金额：
    $87.6万
  • 财政年份：
    2018
  • 负责人：
    Prof Alpha Yap
  • 依托单位：
海外基金